Evidence map›Paper›PMID 40354171›Full record

ArticleThe American journal of bioethics : AJOB2026

Mitigating Bias in Machine Learning Models with Ethics-Based Initiatives: The Case of Sepsis.

John D Banja, Yao Xie, Jeffrey R Smith, Shaheen Rana, Andre L Holder

Abstract read
In one paragraph

Article in The American journal of bioethics : AJOB, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

John D BanjaEmory University.
Yao XieGeorgia Institute of Technology.
Jeffrey R SmithGeorgia Institute of Technology.
Shaheen RanaEmory University.
Andre L HolderEmory University School of Medicine.

Funding

Characterizing patients at risk for sepsis through Big Data (Supplement)K23GM137182 · NIGMS · EMORY UNIVERSITY · PI HOLDER, ANDRE L · 2020 to 2023
$907k
NIGMS NIH HHS K23 GM137182
6 · The paper itself

Abstract

This paper discusses ethics-based strategies for mitigating bias in machine learning models used to predict sepsis onset. The first part discusses how various kinds of bias and their potential synergies can reduce predictive accuracy, especially as those biases derive from social determinants of health (SDOHs) and from the design and construction of the predictive model. The second part of the essay discusses how certain ethically-based strategies might mitigate the potential for disparate or unfair treatment produced by these models, not only as they might apply to sepsis but to any syndrome that witnesses the impact of adverse SDOHs on socioeconomically disadvantaged or marginalized populations.

Indexed as

Machine LearningSepsisSocial Determinants of HealthBiasHumansBiasequityethicsmachine learningsepsissocial determinants of health

Identifiers

PMID40354171
PMCPMC12353398

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.