Evidence map›Paper›PMID 40354169›Full record

ArticleVirulence2025

Tamdy virus pathogenesis in immunocompetent and immunocompromised mouse models.

Mingxue Cui, Hua-Chen Zhu, Xiurong Wang, Ying Cao, Di Liu, Michael J Carr, Yi Guan, Hong Zhou, Weifeng Shi

Abstract read
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingxue CuiSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, China.
Hua-Chen ZhuState Key Laboratory of Emerging Infectious Diseases, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Xiurong WangSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, China.
Ying CaoCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.
Di LiuCAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0003-3693-2726
Michael J CarrNational Virus Reference Laboratory, University College Dublin, Dublin, Ireland.
Yi GuanState Key Laboratory of Emerging Infectious Diseases, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Hong ZhouSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, China.
Weifeng ShiSchool of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, China.ORCID 0000-0002-8717-2942

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tamdy virus (TAMV) is one of the zoonotic tick-borne bunyaviruses that have emerged as global public health threats in recent decades. To date, however, TAMV pathogenesis remains poorly understood. In the present study, we have established different mouse infection models to enable investigation of TAMV pathogenesis. Adult BALB/c mice did not exhibit obvious clinical symptoms or signs post-TAMV infection. In contrast, adult type I interferon receptor knockout (IFNAR

Indexed as

Bunyaviridae InfectionsImmunocompromised HostAnimalsAntibodies, ViralCytokinesDisease Models, AnimalFemaleImmunocompetenceLiverMiceMice, Inbred BALB CMice, KnockoutReceptor, Interferon alpha-betaRNA, ViralViral LoadAntibodies, ViralCytokinesReceptor, Interferon alpha-betaRNA, ViralbunyavirusIFNAR−/− micemouse modelpathogenesisTamdy virus

Identifiers

PMID40354169
PMCPMC12077439

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.