Evidence map›Paper›PMID 40353983›Full record

ArticleEuropean journal of nutrition2025

Assessment of oxidative balance score with hypertension and arterial stiffness in children and adolescents: NHANES 2001-2018.

Che Wang, Rujie Zheng, Xiaoyu Du, Wenjuan Song, Xiaotong Sun, Zhihao Liu, Chengzhi Lu

Abstract read
In one paragraph

Article in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Che WangSchool of Medicine, Nankai University, Tianjin, China.
Rujie ZhengDepartment of Cardiology, Tianjin First Center Hospital, Tianjin, China.
Xiaoyu DuDepartment of Cardiology, Tianjin First Center Hospital, Tianjin, China.
Wenjuan SongDepartment of Cardiology, Tianjin First Center Hospital, Tianjin, China.
Xiaotong SunDepartment of Cardiology, Tianjin First Center Hospital, Tianjin, China.
Zhihao LiuSchool of Medicine, Nankai University, Tianjin, China.
Chengzhi LuSchool of Medicine, Nankai University, Tianjin, China. 5020200072@nankai.edu.cn.

Funding

National Natural Science Foundation of China 81970303National Natural Science Foundation of China 82470294the Natural Science Foundation of Tianjin 21JCYBJC00250Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK-054B
6 · The paper itself

Abstract

objectiveTo investigate the complex relationship between oxidative balance score (OBS), hypertension (HTN) and arterial stiffness in children and adolescents utilizing data gathered from the National Health and Nutrition Examination Survey (NHANES). STUDY

designThrough utilizing NHANES data (2001-2018), OBS, comprising dietary and lifestyle components, was calculated and categorized into tertiles. The correlation between OBS and HTN was explored employing weighted multivariate logistic regression. Stratified analyses were further performed to evaluate the associations across different subgroups.

resultsA total of 11,754 children and adolescents were ultimately enrolled in analyses. High OBS tertiles demonstrated a consistent negative association with HTN across models. Compared with the lowest OBS tertile, the risk of HTN in the highest OBS tertile was decreased by 37% (95% CI 0.44-0.90, p = 0.011). After dividing OBS into dietary OBS and lifestyle OBS, Lifestyle OBS exhibited a significant inverse association with HTN, while dietary OBS showed no significant correlation. Stratified analyses notably revealed the protective impacts of OBS on the risk of HTN in males. Restricted cubic spline analysis confirmed a nonlinear association between OBS and HTN. Moreover, the elevated OBS was significantly associated with decreased ePWV, indicating a potential link between arterial stiffness and OBS.

conclusionIn summary, the risk of HTN was inversely correlated with high OBS. Adopting a wholesome lifestyle enriched with antioxidants to boost OBS may help shield children from HTN risk.

Indexed as

HypertensionOxidative StressVascular StiffnessAdolescentChildCross-Sectional StudiesDietFemaleHumansLife StyleMaleNutrition SurveysRisk FactorsArterial stiffnessChildren and adolescentsHypertensionOxidative balance scoreOxidative stress

Identifiers

PMID40353983
PMCPMC12069149

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.