Evidence map›Paper›PMID 40353922›Full record

ArticleDiscover oncology2025

Application of ultrasound-guided microwave ablation combined with polidocanol injection in benign cystic-solid thyroid nodules and recurrence analysis.

Sichen Yang, Dali Huang

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sichen YangDepartment of Ultrasonography, The First Hospital of Changsha, No. 311 Yingpan Road, Kaifu District, Changsha, 410000, Hunan, China. duyangen479252@163.com.
Dali HuangDepartment of Orthopedics/Ward 21, The Third Hospital of Changsha, Changsha City, 410015, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study is intended to investigate the efficacy of ultrasound-guided microwave ablation (MWA) combined with polyguinol injection in treating benign cystic-solid thyroid nodules and its effect on recurrence rates.

methodsA retrospective analysis was conducted on 120 patients with benign cystic-solid thyroid nodules, who were divided into two groups based on different treatment modalities: the control group (60 cases) and the observation group (60 cases). The control group underwent ultrasound-guided MWA combined with anhydrous ethanol sclerotherapy, while the observation group received ultrasound-guided MWA combined with polidocanol sclerotherapy. Treatment efficacy was assessed postoperatively. Serum levels of free triiodothyronine (FT3), free thyroxine (FT4), and thyroid-stimulating hormone (TSH)were measured before and after surgery. Changes in nodule volume and volume reduction rates were compared. The incidence of adverse reactions and recurrence rates were recorded.

resultsThe observation group demonstrated a significantly higher overall treatment efficacy compared to the control group (P < 0.05). There were no significant differences in preoperative and postoperative FT3, FT4, and TSH levels between the two groups, indicating preserved thyroid function. Postoperative thyroid nodule volumes were significantly reduced in both groups compared to pre-treatment values, with the observation group achieving greater reductions than the control group (P < 0.05). The volume reduction rate was also notably higher in the observation group (P < 0.05). Additionally, the observation group experienced a lower incidence of adverse reactions and recurrence compared to the control group (P < 0.05).

conclusionUltrasound-guided MWA combined with polidocanol injection is more effective in treating benign cystic-solid thyroid nodules. This approach accelerates nodule ablation, significantly reduces nodule size, preserves thyroid function, lowers recurrence rates, and enhances overall safety.

Indexed as

Benign cystic-solid thyroid noduleMicrowave ablationPolidocanolRecurrenceUltrasound-guide

Identifiers

PMID40353922
PMCPMC12069188

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.