ArticleEuropean radiology2025
Internal auditory meatus vascular loops and vestibulocochlear neurovascular contact on MRI: Are they associated with pulsatile tinnitus?
Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesTo compare the presence of internal auditory meatus vascular loops (IVLs) or vestibulocochlear neurovascular contact (CN8-NVC) between unexplained unilateral pulsatile tinnitus (PT) ears and contralateral asymptomatic ears. Furthermore, to investigate whether IVL depth or angulation, or CN8-NVC location is associated with the presence of PT. MATERIALS AND
methodsSingle-centre retrospective case-controlled study of patients undergoing three-dimensional T2-weighted MRI for unexplained unilateral PT from January 2012 to July 2021. Two blinded observers recorded the presence of IVLs or CN8-NVCs, whilst evaluating IVL depth and angulation. Proportions of ears with IVLs or CN8-NVCs were compared between PT ears and contralateral control ears with McNemar's test. Mann-Whitney U or Student's t-test compared the depth and angulation of IVLs and the location of CN8-NVC with respect to the transition zone between ears with and without PT.
resultsThree hundred thirty-seven patients were evaluated (250 female; mean age 47 ± 16 years). There was no significant difference between the proportion of IVLs (19.3% vs 25.2%; p = 0.06) or CN8-NVCs (59.9% vs 65.6%; p = 0.12) in PT ears as compared to contralateral control ears. There was no significant difference in IVL depth (median loop-fundus distance 6.5 mm vs 6.8 mm; p = 0.45), IVL angulation (median interlimb distance 3.1 mm vs 3.3 mm; p = 0.54), or CN8-NVC location within the transition zone (p = 0.58) between ears with and without PT.
conclusionUnexplained unilateral PT is not associated with the presence of an ipsilateral IVL or CN8-NVC. Likelihood of PT is not influenced by depth or angulation of an ipsilateral IVL, nor by whether CN8-NVC is at the transition zone. KEY POINTS: Question The relevance of internal auditory meatus (IAM) vascular loops or vestibulocochlear NVC in the context of PT remains uncertain. Findings Likelihood of unilateral PT was not influenced by the presence, depth, or angulation of IAM vascular loops, nor by the presence or location of vestibulocochlear NVC. Clinical relevance This study argues against the analysis and reporting of IAM vascular loops or vestibulocochlear NVC in the context of PT, and it gives the clinician confidence to reassure the patient that these are unlikely to be an aetiology.
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