Evidence map›Paper›PMID 40353910›Full record

ArticleCurrent microbiology2025

Identifying the Alkaline Tolerance-Related Genes Through Transcriptome Analysis of Halomonas alkalicola CICC 11012 s.

Lei Zhai, Shuaicheng Mu, Ruina Liu, Rui Liu, Geer Lin, Qi Han, Su Yao

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Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lei ZhaiChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China. zhailei@china-cicc.org.
Shuaicheng MuChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China.
Ruina LiuChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China.
Rui LiuChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China.
Geer LinChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China.
Qi HanChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China.
Su YaoChina Center of Industrial Culture Collection (CICC), China National Research Institute of Food and Fermentation Industries, Beijing, 100015, People's Republic of China. milly@china-cicc.org.

Funding

the Fund of National Microbial Resource Center NO. NMRC-2023-4the Fund of Science and Technology Innovation Program of Sinolight Corporation No.ZQ2022JC-QN02
6 · The paper itself

Abstract

Halomonas alkalicola CICC 11012 s is the strongest alkaliphile in the genus Halomonas. So far, studies have focused on the genome level and functional validation of a single gene, providing an overview and partial analysis of the adaptive mechanisms. As such, the comprehensive adaptations of alkaliphiles to extremely alkaline stress remain largely unclear. Therefore, in this study, the transcriptome profiling of H. alkalicola under neutral and alkaline conditions was compared to explore its global adaptation mechanisms towards pH homeostasis. In addition, the different up-regulated genes of this strain grown at pH 11.0 were compared with those grown at pH 7.0. The results revealed that the up-regulated genes were mainly distributed in six categories, including glycosyl transferase, fimbrial assembly protein, TonB-dependent transport system, C

Indexed as

AlkaliesHalomonasAdaptation, PhysiologicalBacterial ProteinsGene Expression ProfilingGene Expression Regulation, BacterialHydrogen-Ion ConcentrationStress, PhysiologicalTranscriptomeAlkaliesBacterial Proteins

Identifiers

PMID40353910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.