Evidence map›Paper›PMID 40353827›Full record

Trial reportEinstein (Sao Paulo, Brazil)2025

Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial.

Laís Renata Almeida Cezário Santos, Anderson Taíra, Rosana de Fátima Possobon, Marcelo de Castro Meneghim, Chien-Lin Su, Paola Lavin, Soham Rej, Gláucia Maria Bovi Ambrosano, Karine Laura Cortellazzi

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Einstein (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laís Renata Almeida Cezário SantosDepartment of Health Sciences and Children's Dentistry, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, SR Brazil.ORCID http://orcid.org/0000-0002-0737-2857
Anderson TaíraSociedade Brasileira de Tai Chi Chuan e Cultura Oriental, Piracicaba, SR Brazil.ORCID http://orcid.org/0000-0001-8805-5847
Rosana de Fátima PossobonDepartment of Health Sciences and Children's Dentistry, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, SR Brazil.ORCID http://orcid.org/0000-0001-6179-3030
Marcelo de Castro MeneghimDepartment of Health Sciences and Children's Dentistry, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, SR Brazil.ORCID http://orcid.org/0000-0003-2673-3627
Chien-Lin SuDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-0664-8583
Paola LavinDepartment of Psychiatry, The Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-0733-9261
Soham RejDepartment of Psychiatry, The Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-3908-9124
Gláucia Maria Bovi AmbrosanoDepartment of Health Sciences and Children's Dentistry, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, SR Brazil.ORCID http://orcid.org/0000-0001-5950-6370
Karine Laura CortellazziDepartment of Health Sciences and Children's Dentistry, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, SR Brazil.ORCID http://orcid.org/0000-0001-9584-9477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigated the effects of Tai Chi/Qigong practice over 13 weeks on anxiety and perceived stress levels in middle-aged or older Brazilian hypertensive and diabetic individuals assisted in a primary healthcare setting.

methodsNinety-one patients with diabetes mellitus and/or hypertension diagnosed and followed up at a primary care center were randomized to the Tai Chi/Qigong intervention (n = 45) or waitlist (n = 46) group for 13 weeks. Outcome measures were collected at baseline and at 6 and 13 weeks for anxiety (State-Trait Anxiety Inventory [STAI]) and stress (Perceived Stress Scale - PSS14). The primary endpoint of the study was 13 weeks. We used a linear mixed-effects model to analyze the primary and secondary outcomes, considering the treatment group and time as covariates and treating the subject as a random effect.

resultsOf the included 91 participants, 53 completed the 6-week assessment, and 42 completed the 13-week assessment. After 13 weeks, the Tai Chi/Qigong Group had lower scores for anxiety (STAI Estimate = -6.421; SD = 2.679; 95% confidence interval (95%CI) = [-11.615,-1.224]; p = 0.018) and stress (PSS14 Estimate = -9.290; SD= 2.262; 95%CI= [-13.678,-4.906]; p<0.001).

conclusionA 13-week Tai Chi/Qigong intervention was efficacious in lowering anxiety and perceived stress scores in middle-aged and older patients with diabetes mellitus and hypertension and can potentially be used in primary care centers as an adjunct therapy.Trial registration: Brazilian Registry of Clinical Trials (ReBEC), Identifier: U1111-1276-1787.

Indexed as

AnxietyDiabetes MellitusHypertensionQigongStress, PsychologicalTai JiAgedBrazilFemaleHumansMaleMiddle AgedTime FactorsTreatment Outcome

Identifiers

PMID40353827
PMCPMC12002851

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.