Evidence map›Paper›PMID 40353780›Full record

ArticleThe Journal of cell biology2025

Anillin links up with RhoA to break the symmetry of cytokinetic ring closure.

Guillaume D Chambaud, Vlad C Martin, Gilles R X Hickson

Abstract read
In one paragraph

Article in The Journal of cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guillaume D ChambaudCHU Sainte-Justine Research Center , Montréal, Canada.ORCID 0009-0001-4916-3068
Vlad C MartinCHU Sainte-Justine Research Center , Montréal, Canada.ORCID 0009-0000-2555-6513
Gilles R X HicksonCHU Sainte-Justine Research Center , Montréal, Canada.ORCID 0000-0001-7670-9815

Funding

CIHR MOP-97788Natural Sciences and Engineering Research Council RGPIN-2021-03324
6 · The paper itself

Abstract

During animal cell cytokinesis, active RhoA assembles actomyosin-based contractile rings that tend to close asymmetrically. Through imaging C. elegans zygotes, Lebedev et al. (https://doi.org/10.1083/jcb.202405182) reveal that the scaffold protein, anillin, promotes asymmetric ring closure by locally sequestering RhoA from its canonical effectors and thereby limiting actomyosin contractility.

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsContractile ProteinsCytokinesisrhoA GTP-Binding ProteinActomyosinAnimalsActomyosinanillinCaenorhabditis elegans ProteinsContractile ProteinsrhoA GTP-Binding Protein

Identifiers

PMID40353780
PMCPMC12077230

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.