ArticleTurkish archives of pediatrics2025
Subclinical Enthesitis in Children with Chronic Nonbacterial Osteomyelitis.
Article in Turkish archives of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Chronic Recurrent Multifocal Osteomyelitis in a Pediatric Patient: An Uncommon Case With Diagnostic Challenge.Clinical case reports · 2026Article
- Inflammatory ankle MRI findings in pediatric and young adult patients with familial Mediterranean fever: a comparison with juvenile idiopathic arthritis and chronic nonbacterial osteomyelitis.Skeletal radiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Enthesitis is rare in chronic nonbacterial osteomyelitis (CNO) compared to enthesi- tis-related arthritis. It may be asymptomatic in CNO patients. This study aimed to evaluate the presence of subclinical enthesitis in patients with CNO using ultrasonography (US). Materials and Methods: Patients with CNO were included in this study and evaluated with US by an expert pediatric radiologist. The entheses of 7 tendons were assessed bilaterally, includ- ing the common extensor and flexor tendons, the quadriceps tendon, the proximal and distal patellar tendons, the Achilles tendon, and the plantar fascia. Results: Fifty CNO patients were included. The median age of the patients was 12.4 years, and 58% were female. Subclinical enthesitis was identified in 3 patients (6%). These 3 patients were male, older than 6 years at diagnosis, had bilateral sacroiliitis, and were positive for human leukocyte antigen-B27. The enthesitis was located in the right quadriceps, right plantar fascia, and bilateral Achilles. One of these patients also had a clinical history of enthesitis at diagnosis. Treatment modification was not done when subclinical enthesitis was detected since they were in clinical remission and acute phase reactants were within normal limits. However, the patient with bilateral subclinical Achilles enthesitis had a disease flare afterward, and methotrexate was switched to etanercept. Conclusion: Subclinical enthesitis can be observed especially in CNO patients with overlappin- genthesitis-related arthritis features. The use of US may prove beneficial in detecting subclini- cal enthesitis and predicting disease flare.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.