Evidence map›Paper›PMID 40353559›Full record

Observational studyJournal of cosmetic dermatology2025

Single Session of Calcium Hydroxylapatite, Incobotulinumtoxin A, and Hyaluronic Acid for Gluteal Aesthetic Improvement.

David Di Sessa, Carla de Sanctis Pecora, Rossana Cantanhede Farias de Vasconcelos, Gustavo Limongi Moreira

Abstract readObservational Study
In one paragraph

Observational study in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David Di SessaDSL Clinica, Private Practice, São Paulo, Brazil.ORCID https://orcid.org/0009-0006-5534-4267
Carla de Sanctis PecoraClinica Dermatologie, Private Practice, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-0711-281X
Rossana Cantanhede Farias de VasconcelosDepartment of Dermatology, Universidade de Santo Amaro, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-6185-1840
Gustavo Limongi MoreiraDSL Clinica Medica, Private Practice, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9864-5277

Funding

Merz Pharmaceuticals
6 · The paper itself

Abstract

backgroundWhile various techniques exist to treat the buttocks, few combine multiple products in a single session, offering both aesthetic and logistical benefits.

aimsTo evaluate the aesthetic improvement of the buttocks in patients treated with a combination of calcium hydroxylapatite-carboxymethylcellulose (CaHA-CMC), Incobotulinumtoxin A (IncoBoNT-A), and cohesive poly-densified matrix hyaluronic acid (CPM-HA V) in one session. PATIENTS/

methodsThis retrospective observational study involved women aged from 35 to 55 years who underwent the combined technique. Data were collected from the patient's charts, and photos were taken before treatment, and at 30 and 90 days post-procedure. Two independent physicians evaluated cellulite (5-point scale) and flaccidity (4-point scale) in all patients. Aesthetic improvements were assessed by patients and physicians using the GAIS (5-point) scale.

resultsTen women aged 45.3 (±5.2) years participated. Initially, 80% presented moderate to severe flaccidity, and 30% and 90% presented moderate to very severe cellulite in relaxed and contracted buttocks, respectively. After 90 days, flaccidity improved in 9/10 patients, and cellulite in 4/10 and 9/10 patients in static and dynamic assessments, respectively. There was a moderate correlation between the assessments at baseline and after 90 days. The aesthetic appearance of the buttocks was rated as much improved or very much improved by 100% of the patients and 60% of the physicians after 90 days.

conclusionA single-session combined application of CaHA-CMC, IncoBoNT-A, and CPM-HA effectively improved flaccidity and cellulite, resulting in high patient satisfaction.

Indexed as

Botulinum Toxins, Type ACelluliteCosmetic TechniquesDermal FillersDurapatiteHyaluronic AcidAdultButtocksCarboxymethylcellulose SodiumEstheticsFemaleHumansMiddle AgedPatient SatisfactionRetrospective StudiesSkin AgingBotulinum Toxins, Type ACarboxymethylcellulose SodiumDermal FillersDurapatiteHyaluronic AcidincobotulinumtoxinAagingbuttockscalcium hydroxylapatitehyaluronic acidincobotulinum toxin Asagging

Identifiers

PMID40353559
PMCPMC12067859

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.