Evidence map›Paper›PMID 40353484›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2025

Utility of MRI quantitative analysis in assessment of audio-vestibular impairment.

Rosalinda Calandrelli, Fabio Pilato, Pasqualina Maria Picciotti, Giorgia Rossi, Marco Panfili, Giovanni Mazzon, Angelo Tizio, Daniela Rodolico, Simona Gaudino, Jacopo Galli

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Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rosalinda CalandrelliRadiology and Neuroradiology Unit, Department of Imaging, Radiation Therapy and Hematology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Fabio PilatoFondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Pasqualina Maria PicciottiDepartment of Head, Neck and Sensory Organs, Università Cattolica del Sacro Cuore, Rome, Italy.
Giorgia RossiUnit of Otorhinolaryngology and Head and Neck Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Marco PanfiliRadiology and Neuroradiology Unit, Department of Imaging, Radiation Therapy and Hematology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Giovanni MazzonRadiology and Neuroradiology Unit, Department of Imaging, Radiation Therapy and Hematology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Angelo TizioDepartment of Head, Neck and Sensory Organs, Università Cattolica del Sacro Cuore, Rome, Italy.
Daniela RodolicoDepartment of Head, Neck and Sensory Organs, Università Cattolica del Sacro Cuore, Rome, Italy.
Simona GaudinoRadiology and Neuroradiology Unit, Department of Imaging, Radiation Therapy and Hematology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy.
Jacopo GalliDepartment of Head, Neck and Sensory Organs, Università Cattolica del Sacro Cuore, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To quantify inner ear fluid changes in patients with audiovestibular deficits by measuring signal intensity values; to correlate the signal intensity values of inner ear structures and audio-vestibular impairment severity. Methods: 26 patients with unilateral vestibulocochlear deficits underwent hearing and vestibular assessments and were categorised into severity classes using audiological and vestibular deficit scores. Normalised signal intensity values of inner ear structures were extracted from 3D-T2-WI-MRI scans (nT2mean, nT2Max, nT2min) and signal intensity ratios were calculated using the unaffected ear as a reference. Results: Asymmetry ratios of nT2Max and nT2mean volumetric intensity values from the cochlea and entire inner ear discriminated severe hearing impairment from lesser deficits and diagnostic performance of nT2mean values was excellent. Conclusions: Quantitative MRI analysis may be a useful tool to assess the severity of auditory deficits. Asymmetry ratios of nT2mean and nT2Max signal intensity values derived from the cochlea and entire inner labyrinth are surrogate indicators of unilateral cochlear-vestibular deficits and may have potential prognostic value.

Indexed as

Magnetic Resonance ImagingVestibular DiseasesAdultAgedFemaleHumansMaleMiddle AgedSeverity of Illness IndexYoung Adultaudio-vestibular dysfunctioninner earMRIquantitative analysis

Identifiers

PMID40353484
PMCPMC12068521

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.