Evidence map›Paper›PMID 40353483›Full record

GuidelineActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2025

Cochlear Implant (CI) procedure. Italian Clinical Practice Guidelines of the Italian Society of Otorhinolaryngology (SIOeChCF) and Italian Society of Audiology and Phoniatrics (SIAF). Part 2: cochlear implants in children.

Domenico Cuda, Stefano Berrettini, Silvia Minozzi, Franca Artioli, Umberto Barbieri, Cristian Borghi, Eliana Cristofari, Giorgio Conte, Davide Cornolti, Diego di Lisi and 15 more

Abstract readPractice Guideline
In one paragraph

Guideline in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cochlear implantation before age one or after: cognitive flexibility, planning, and problem-solving in pediatric recipients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Domenico CudaDepartment of Otolaryngology, AUSL Piacenza, Italy.
Stefano BerrettiniUO Otolaryngology, Audiology and Phoniatrics Unit, University of Pisa, Pisa, Italy.
Silvia MinozziLaboratory of Methodology of Systematic Reviews and Production of Guidelines. Istituto di Ricerche Farmacologiche Mario Negri, IRCCS, Milan, Italy.
Franca ArtioliDepartment of Otolaryngology-Head Neck Surgery, University Hospital of Modena, Modena, Italy.
Umberto BarbieriPatient representative.
Cristian BorghiAmplifon Italia S.p.A.
Eliana CristofariENT Audio-Vestibology Unit, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Giorgio ConteNeuroradiology Unit, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milan, Italy.
Davide CornoltiAssociazione per la Sordità ed Impianti Cocleari - ODV (A.S.I.C.-ODV), Lucca, Italy.
Diego di LisiENT Department, Martini Hospital, Turin, Italy.
Anna Rita FetoniDepartment of Neuroscience, Reproductive Science and Dentistry, Section of Audiology, University of Naples "Federico II", Naples, Italy.
Simona FioriNeuroscience Department, Meyer Children's Hospital, Florence, Italy.
Elisabetta GenoveseDepartment of Maternal and Child and Adult Medical and Surgical Sciences, University of Modena and Reggio Emilia.
Giorgia GirottoDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Marinella MajoranoDepartment of Human Sciences, University of Verona, Italy.
Pasquale MarsellaAudiology and Otosurgery Department, "Bambino Gesù" Children's Hospital, Rome, Italy.
Emanuele MarzettiFondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.
Maria NicastriDepartment of Sense Organs, University Sapienza of Rome, Rome, Italy.
Gaetano PaludettiDepartment of Head, Neck and Sensory Organs, Catholic University of The Sacred Heart, Rome, Italy.
Nicola QuarantaOtolaryngology Unit, Department of Translational Biomedicine and Neurosciences (DiBraiN), University "Aldo Moro" of Bari, Italy.
Patrizia TrevisiSection of Otorhinolaryngology-Head and Neck Surgery, Department of Neurosciences, University of Padua, Padua, Italy.
Diego ZanettiAudiology Unit, Department of Specialistic Surgical Sciences, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Michela CinquiniLaboratory of Methodology of Systematic Reviews and Production of Guidelines. Istituto di Ricerche Farmacologiche Mario Negri, IRCCS, Milan, Italy.
Sara GhiselliDepartment of Otolaryngology, AUSL Piacenza, Italy.
Francesca ForliUO Otolaryngology, Audiology and Phoniatrics Unit, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Cochlear implant (CI) is a well-established treatment for children with sensorineural hearing loss without benefit from hearing aids. The Italian guidelines date back 15 years; given the expansion of indications for CI (including single side deafness and asymmetrical hearing loss) it became necessary to establish updated guidelines. Methods: Thirteen experts and 2 patient representatives selected the key questions and drew up recommendations. The document was developed following the GRADE methodology. The methodological team of the Mario Negri Pharmacological Research Institute performed systematic reviews for each question and supported the overall process. Results: Four key questions were identified and recommendation formulated, with subgroups and implementation considerations. Conclusions: Though the systematic research of scientific literature found a scarcity of randomised trials and an overall poor conduct and reporting quality of primary studies and systematic reviews, conditional recommendations in favour of CI have been formulated for different subgroups of children. Further studies should enrol a larger number of participants and use consistent instruments to evaluate hearing outcomes, in order to increase comparability of results and data pooling through meta-analysis.

Indexed as

Cochlear ImplantationCochlear ImplantsHearing Loss, SensorineuralChildHumansItalychildrenclinical practice guidelinecochlear implanthearing loss

Identifiers

PMID40353483
PMCPMC12068519

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.