Evidence map›Paper›PMID 40353472›Full record

Observational studyCurrent drug safety2026

Optimizing Antibiotic Use and Awareness in Hospitals: Establishing Effective Antimicrobial Stewardship Pathways.

Bianca Maria Donida, Grazia Mingolla, Antonio Manfredi

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Current drug safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bianca Maria DonidaASST Bergamo Ovest, Piazzale Ospedale Meneguzzo, Treviglio, (BG), 1, 24047, Italy.
Grazia MingollaASST Bergamo Ovest, Piazzale Ospedale Meneguzzo, Treviglio, (BG), 1, 24047, Italy.
Antonio ManfrediASST Bergamo Ovest, Piazzale Ospedale Meneguzzo, Treviglio, (BG), 1, 24047, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntibiotic resistance poses a significant challenge in healthcare, requiring effective management of antibiotic use. This study examines systemic antibiotic consumption at ASST Bergamo Ovest, a northern Italian hospital, from January 2022 to June 2023, with a focus on Healthcare-Associated Infections (HAIs) and prescription appropriateness. This retrospective observational study aims to analyze antibiotic usage trends and to evaluate prescribing practices against national guidelines.

methodsData on systemic antibiotic consumption were reviewed, categorized by the AWaRe classification system (Access, Watch, Reserve), and analyzed using the Defined Daily Dose per 100 patient-days metric.

resultsThe study observed a 7% overall reduction in antibiotic use, including a 5% decrease in the AWaRe Watch category. Despite this progress, the appropriateness of prescribing remained consistently low. These findings suggest partial alignment with the Italian Plan against Antibiotic Resistance but highlight the need for improvement in prescribing practices. DISCUSSION: While ASST Bergamo Ovest has reduced antibiotic consumption and the use of higher-risk antibiotics, low prescribing appropriateness underscores the need for enhanced realtime monitoring and more effective stewardship programs.

conclusionTargeted interventions are essential to improve prescribing practices, combat multidrug- resistant infections, and meet European antibiotic stewardship standards.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipCross InfectionHospitalsPractice Patterns, Physicians'Drug UtilizationHumansItalyRetrospective StudiesAnti-Bacterial AgentsAntibiotic resistanceantibiotic stewardshipantimicrobial managementhealthcareassociated infectionsmultidrug-resistant infections.prescribing awareness

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.