Evidence map›Paper›PMID 40353422›Full record

ReviewCurrent pharmaceutical design2025

Emerging Trends in the Pharmacological and Therapeutic Potential of Ginger: From Traditional Medicine to Nanotechnological Innovations.

Jitendra Gupta, Devesh Kumar, Reena Gupta, Sumant Kumar, Mohit Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pharmaceutical design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Green-Synthesized Silver Nanoparticles fromNanomaterials (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jitendra GuptaInstitute of Pharmaceutical Research, GLA University, District Mathura, U.P. 281406, India.
Devesh KumarInstitute of Pharmaceutical Research, GLA University, District Mathura, U.P. 281406, India.
Reena GuptaInstitute of Pharmaceutical Research, GLA University, District Mathura, U.P. 281406, India.
Sumant KumarDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Badal Road, Bathinda, 151001, Punjab, India.
Mohit KumarDepartment of Pharmaceutical Sciences and Technology, Maharaja Ranjit Singh Punjab Technical University, Badal Road, Bathinda, 151001, Punjab, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGinger (Zingiber officinale) has a long history as a culinary and medicinal plant, widely recognized in traditional medicine for the treatment of various diseases. In recent years, advances in nanotechnology have provided innovative delivery systems, enhancing ginger's bioavailability and efficacy in modern therapeutic applications. This study aims to explore ginger's pharmacological and therapeutic potential, tracing its evolution from traditional medicine to its integration into modern nanotechnological innovations. By analysing emerging trends, this study seeks to highlight ginger's diverse bioactivities and its potential to enhance therapeutic efficacy through advanced delivery systems.

methodsLiterature was searched from various databases, mainly from 1984 to 2024, such as Scopus, Web of Science, Google Scholar, PubMed and Science Direct using keywords including "Ginger", "Zingiber officinale", "Gingerols", "Shogaols", "Paradols" and "Nanocarriers" and their combination. This study examines the therapeutic potential of ginger by reviewing its traditional applications and exploring nanotechnological innovations in ginger-based drug delivery systems. Nanoemulsions, liposomes, and nanoparticles were assessed for their ability to improve the stability, bioavailability, and targeted delivery of ginger's bioactive compounds.

resultsGinger's bioactive constituents, including gingerols, shogaols, and paradols, exhibited significant pharmacological activities, including anti-inflammatory, antioxidant, anticancer, antidiabetic, and gastroprotective effects. Nano-based delivery systems have shown improved stability, controlled release, and targeted delivery, thereby maximising therapeutic efficacy in treating various diseases.

conclusionGinger holds significant therapeutic promise in both traditional and modern medicine, mainly when used with nanotechnology for improved bioavailability and efficacy. These findings support the development of ginger-based treatments as complementary therapies in holistic healthcare. Further research and clinical trials are essential to validate these applications and optimize dosages for clinical use.

Indexed as

Medicine, TraditionalNanotechnologyPlant ExtractsZingiber officinaleAnimalsDrug Delivery SystemsHumansPlant ExtractsGingergingerolsnanocarriers system.paradolsshogaolsZingiber officinale

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.