Evidence map›Paper›PMID 40353351›Full record

ArticleeLife2025

Jiro Yoshino, Sonali S Mali, Claire R Williams, Takeshi Morita, Chloe E Emerson, Christopher J Arp, Sophie E Miller, Chang Yin, Lydia Thé, Chikayo Hemmi and 5 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Heat-off responses of epidermal cells sensitizebioRxiv : the preprint server for biology · 2025
    Article
  6. eLife · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Jiro Yoshino *Department of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0001-9761-4882
Sonali S Mali *Division of Education, Marine Biological Laboratory, Woods Hole, United States.ORCID https://orcid.org/0000-0003-0737-813X
Claire R Williams *Department of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0001-5467-149X
Takeshi MoritaDivision of Education, Marine Biological Laboratory, Woods Hole, United States.ORCID https://orcid.org/0000-0002-8570-6744
Chloe E EmersonDivision of Education, Marine Biological Laboratory, Woods Hole, United States.ORCID https://orcid.org/0000-0003-1188-0501
Christopher J ArpDivision of Education, Marine Biological Laboratory, Woods Hole, United States.ORCID https://orcid.org/0000-0002-5059-6178
Sophie E MillerDivision of Education, Marine Biological Laboratory, Woods Hole, United States.ORCID https://orcid.org/0000-0001-6805-7036
Chang YinDepartment of Biology, University of Washington, Seattle, United States.
Lydia ThéDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID https://orcid.org/0009-0008-0297-776X
Chikayo HemmiDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0002-3815-8164
Mana MotoyoshiDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0005-4759-0065
Kenichi IshiiDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8834-5729
Kazuo EmotoDepartment of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-4194-801X
Diana M BautistaDivision of Education, Marine Biological Laboratory, Woods Hole, United States.ORCID https://orcid.org/0000-0002-6809-8951
Jay Z ParrishDepartment of Biology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0002-0656-9148

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Structural and functional coupling of epidermis to somatosensory neurons in DrosophilaR01NS076614 · NINDS · UNIVERSITY OF WASHINGTON · PI BAUTISTA, DIANA MICHELE, PARRISH, JAY Z · 2011 to 2023
$4.2M
Neurobiology Summer CourseR25NS063307 · NINDS · MARINE BIOLOGICAL LABORATORY · PI Ricardo C Araneda, Michael Blake Hoppa · 2008 to 2026
$3.5M
Identification of proteins that structurally couple epidermal cells to somatosensory neuronsR21NS125795 · NINDS · UNIVERSITY OF WASHINGTON · PI PARRISH, JAY Z, ROGERS, STEPHEN · 2021 to 2021
$442k
Developmental and Molecular Logic of Synaptic Partner SpecificityF31NS106775 · NINDS · UNIVERSITY OF WASHINGTON · PI WILLIAMS, CLAIRE · 2018 to 2019
$75k
Japan Agency for Medical Research and Development JP22gm310010Japan Agency for Medical Research and Development JP22gm6510011Japan Society for the Promotion of Science KAKENHI 16H02504Japan Society for the Promotion of Science KAKENHI 22K06309Ministry of Education, Culture, Sports, Science and Technology KAKENHI 16H06456National Science Foundation Graduate Research Fellowship Program DGE1752814NIH HHS 5F31NS106775NIH HHS P40 OD018537NIH HHS R01NS076614NIH HHS R21NS125795NIH HHS R25NS063307NINDS NIH HHS F31 NS106775NINDS NIH HHS R01 NS076614NINDS NIH HHS R21 NS125795NINDS NIH HHS R25 NS063307
6 · The paper itself

Abstract

Somatosensory neurons (SSNs) that detect and transduce mechanical, thermal, and chemical stimuli densely innervate an animal's skin. However, although epidermal cells provide the first point of contact for sensory stimuli, our understanding of roles that epidermal cells play in SSN function, particularly nociception, remains limited. Here, we show that stimulating

Indexed as

Behavior, AnimalDrosophilaDrosophila melanogasterEpidermal CellsMechanotransduction, CellularNociceptionNociceptorsAnimalsDrosophila ProteinsLarvaDrosophila ProteinsD. melanogasterepidermisgeneticsgenomicsmechanosensationneurosciencenociceptionsomatosensation

Identifiers

PMID40353351
PMCPMC12068870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.