Evidence map›Paper›PMID 40353282›Full record

ArticleKorean journal of neurotrauma2025

Optic Nerve Sheath Diameter Estimation to Detect Increased Intracranial Pressure in Traumatic Brain Injury patients at a Level I Trauma Center in Eastern India.

Abdul Hakeem, Majid Anwer, Abdul Vakil Khan, Harendra Kumar, Venkatesh Karthikeyan, Rachith Sridhar, Anil Kumar, Anurag Kumar, Subhash Kumar

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Korean journal of neurotrauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07786324 (Comparison of 3% Hypertonic Saline Versus 20% Mannitol in Reduction of Increased Intracranial Pressure in Patients With Traumatic Brain Injury Using Optic Nerve Sheath Diameter Measurements''), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07786324 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of 3% Hypertonic Saline Versus 20% Mannitol in Reduction of Increased Intracranial Pressure in Patients With Traumatic Brain Injury Using Optic Nerve Sheath Diameter Measurements''

TypeinterventionalSponsorAssiut UniversityRan2026 to 2029Enrolled100ConditionsTBI (Traumatic Brain Injury), ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter MeasurementArmsMannitol (20%), Hypertonic Saline ( 3% Sodium Chloride Saline)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdul HakeemDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0002-2128-1732
Majid AnwerDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0003-4193-0805
Abdul Vakil KhanDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0009-0004-8138-3695
Harendra KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0009-0000-6646-1449
Venkatesh KarthikeyanDepartment of Community and Family Medicine, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0002-3768-3218
Rachith SridharDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0002-4493-8514
Anil KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0002-8271-5784
Anurag KumarDepartment of Trauma Surgery and Critical Care, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0002-5849-3958
Subhash KumarDepartment of Radiology, All India Institute of Medical Sciences, Patna, India.ORCID https://orcid.org/0000-0001-5940-9490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the diagnostic accuracy of optic nerve sheath diameter (ONSD) measured by ultrasound as a non-invasive marker for detecting elevated intracranial pressure (ICP) in patients with traumatic brain injury (TBI), based on clinical and radiological findings. Methods: This diagnostic accuracy study included 180 adult patients with isolated TBI admitted to a Level I Trauma Centre in Eastern India. ONSD was measured bilaterally using a 7.5 MHz linear ultrasound probe, 3 mm posterior to the globe. Clinical and radiological parameters were recorded, and increased ICP was determined based on a predefined clinical signs and computed tomography findings. Statistical analysis included logistic regression and receiver operating characteristic (ROC) curve analysis using Jamovi software. Results: The mean ONSD was significantly higher in patients with increased ICP (5.36±0.56 mm) compared to those without (4.13±0.34 mm, Conclusion: Ultrasound-measured ONSD is a sensitive, non-invasive bedside tool for detecting increased ICP in TBI patients, particularly useful in resource-limited settings.

Indexed as

Glasgow Coma ScaleIntracranial pressureOptic nerveTraumatic brain injuryUltrasonography

Identifiers

PMID40353282
PMCPMC12062819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.