Evidence map›Paper›PMID 40352928›Full record

ReviewFrontiers in immunology2025

CD4

Zhengqi Lian, Ying Luo, Yina Li, Yikun Gao, Xiaoxing Xiong, Lijuan Gu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhengqi Lian *Central Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Ying Luo *Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, China.
Yina LiCentral Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Yikun GaoCentral Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.
Xiaoxing XiongDepartment of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, China.
Lijuan GuCentral Laboratory, Renmin Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke (IS) is a significant contributor to disability and death worldwide, with limited treatments beyond early intervention. The importance of CD4

Indexed as

CD4-Positive T-LymphocytesIschemic StrokeAnimalsHumansCD4+ T cellsinflammatory responsesischemic strokeTh17 cellstherapeutic targetTreg cells

Identifiers

PMID40352928
PMCPMC12061934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.