Evidence map›Paper›PMID 40352805›Full record

ArticleTobacco induced diseases2025

Comparative assessment of respiratory, hematological and inflammatory profiles of long-term users of cigarettes, shisha, and e-cigarettes in Saudi Arabia.

Mazen M Homoud, Rowaida Qoutah, Gokul Krishna, Noran Harbli, Layan Saaty, Afrah Obaidan, Abdulrahman Alkhathami, Noran Jamil, Tala M Alkayyat, Maryam Alsughayyir and 9 more

Abstract read
In one paragraph

Article in Tobacco induced diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Mazen M HomoudDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Rowaida QoutahDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Gokul KrishnaDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Noran HarbliDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Layan SaatyDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Afrah ObaidanDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Abdulrahman AlkhathamiDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Noran JamilDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Tala M AlkayyatDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Maryam AlsughayyirDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Nada GubariDepartment of Respiratory Therapy, Batterjee Medical College, Jeddah, Saudi Arabia.
Saleh AlkhathamiDepartment of Medical Laboratory, King Fahad Armed Hospital, Jeddah, Saudi Arabia.
Ali AlqarniDepartment of Medical Laboratory, King Fahad Armed Hospital, Jeddah, Saudi Arabia.
Omar AlqurashiDepartment of Medical Laboratory, King Fahad Armed Hospital, Jeddah, Saudi Arabia.
Khalid AssiriDepartment of Medical Laboratory, King Fahad Armed Hospital, Jeddah, Saudi Arabia.
Khalid Saeed AlwadeaiDepartment of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Wafaa AbdulrahmanDepartment of Microbiology, Batterjee Medical College, Jeddah, Saudi Arabia.
Husam AlahmadiDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Ayedh AlahmariDepartment of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlobally, over 1 billion people smoke, resulting in approximately 8 million deaths each year. Although the health risks associated with traditional cigarettes are extensively documented, there is an increasing need to evaluate the long-term effects of alternative tobacco products, particularly shisha, and e-cigarettes. This study seeks to compare the respiratory, hematological, and inflammatory profiles of long-term users of cigarettes, shisha, and e-cigarettes in Saudi Arabia.

methodsA cross-sectional, observational study was conducted at the Respiratory Therapy laboratories of Batterjee Medical College (BMC), Jeddah, Saudi Arabia, between February 2022 and August 2023. It involved four groups: cigarette smokers, shisha smokers, e-cigarette users, and non-smokers. Pulmonary function tests (PFTs) measured FEV

resultsCigarette and shisha users demonstrated significantly reduced FEV

conclusionsCompared to non-smokers, long-term cigarette and shisha smoking is associated with airway obstructive changes and increased inflammatory responses. Although e-cigarette users demonstrated lower inflammatory markers and less deviation from normal PFT, some exhibited borderline values with airway obstruction. Further research is needed to clarify the long-term health consequences of e-cigarette use.

Indexed as

cigarettese-cigaretteshematologyPFTshisha

Identifiers

PMID40352805
PMCPMC12065132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.