Evidence map›Paper›PMID 40352793›Full record

ArticleBiology methods & protocols2025

A deep learning pipeline for morphological and viability assessment of 3D cancer cell spheroids.

Ajay K Mali, Sivasubramanian Murugappan, Jayashree Rajesh Prasad, Syed A M Tofail, Nanasaheb D Thorat

Abstract read
In one paragraph

Article in Biology methods & protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ajay K MaliDepartment of Physics and Bernal Institute, University of Limerick, Castletroy, Limerick, V94T9PX, Ireland.
Sivasubramanian MurugappanDepartment of Physics and Bernal Institute, University of Limerick, Castletroy, Limerick, V94T9PX, Ireland.
Jayashree Rajesh PrasadComputer Science and Engineering, School of Computing, MIT Art Design and Technology University, Pune, Maharashtra, 412201, India.
Syed A M TofailDepartment of Physics and Bernal Institute, University of Limerick, Castletroy, Limerick, V94T9PX, Ireland.
Nanasaheb D ThoratDepartment of Physics and Bernal Institute, University of Limerick, Castletroy, Limerick, V94T9PX, Ireland.ORCID https://orcid.org/0000-0001-6343-527X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) spheroid models have advanced cancer research by better mimicking the tumour microenvironment compared to traditional

Indexed as

artificial intelligenceconvolutional neural networkdrug discoveryhigh-throughput screeninglive/dead assayspheroid viabilitytoxicologyU-Net

Identifiers

PMID40352793
PMCPMC12064216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.