Crystal Shape Factors of Form I Paracetamol.

Mayank Vashishtha, Juntao Li, Mahmoud Ranjbar, Srinivas Gadipelli, Paul R Shearing, Gavin Walker, K Vasanth Kumar

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Article in Crystal growth & design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Mayank VashishthaDepartment of Chemical Sciences, Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick V94 T9PX, Ireland.

Juntao LiDepartment of Chemical Engineering, University College London, London WC1E 6BT, United Kingdom.

Mahmoud RanjbarDepartment of Chemical Sciences, Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick V94 T9PX, Ireland.

Srinivas GadipelliDepartment of Chemical Engineering, University College London, London WC1E 6BT, United Kingdom.ORCID https://orcid.org/0000-0002-1362-6905

Paul R ShearingDepartment of Chemical Engineering, University College London, London WC1E 6BT, United Kingdom.ORCID https://orcid.org/0000-0002-1387-9531

Gavin WalkerDepartment of Chemical Sciences, Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick V94 T9PX, Ireland.

K Vasanth KumarDepartment of Chemical Sciences, Synthesis and Solid State Pharmaceutical Centre, University of Limerick, Limerick V94 T9PX, Ireland.ORCID https://orcid.org/0000-0003-4244-4542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we report the new protocols that are developed to determine the shape factors of Form I paracetamol crystals using a combination of techniques that rely on the state-of-the-art X-ray computed tomography and Morphologi G3. The determined shape factors successfully predicted the crystal growth rate of paracetamol in 2-propanol and the length of the crystals growing in the supersaturated solution.

Identifiers

PMID40352749

DOI10.1021/acs.cgd.5c00005

PMCPMC12063038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.