Evidence map›Paper›PMID 40352731›Full record

ArticleiScience2025

Laser speckle size and contrast investigation of volumetric scattering from controlled turbid phantoms and mouse skin tissues.

Carla Kulcsar, Daniel C Louie, Alex Vitkin

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carla KulcsarDepartment of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.
Daniel C LouiePrincess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
Alex VitkinDepartment of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential of spatial laser speckle analysis to interrogate scattering properties of volumetric optical tissue-like phantoms and biological tissues is examined. The simple and inexpensive experimental setup consists of a HeNe laser illuminating turbid samples to acquire speckle patterns in backscattering geometry. Theoretical Monte Carlo simulations of subsurface light fluence patterns and scattering statistics are used to interpret the experimental findings, in an effort to help expand established speckle theory from rough surface effects to volumetric scattering processes. Beyond controlled phantom studies, initial results from normal and pathologic biological tissues are also presented and discussed. Building on previous research that attempts to link specific stochastic speckle metrics to medium scattering properties, this study suggests that a combination of speckle contrast and speckle size can be related to varying scattering coefficients, toward distinguishing samples by their underlying scatterer size and concentration.

Indexed as

Biomedical engineeringOpticsPhotonics

Identifiers

PMID40352731
PMCPMC12063137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.