Evidence map›Paper›PMID 40352730›Full record

ArticleiScience2025

Multiple sclerosis severity variant in

Hendrik J Engelenburg, Aletta M R van den Bosch, J Q Alida Chen, Cheng-Chih Hsiao, Marie-José Melief, Adil Harroud, Inge Huitinga, Jörg Hamann, Joost Smolders

Erratum issuedAbstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Observational
  6. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Hendrik J EngelenburgNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.
Aletta M R van den BoschNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.
J Q Alida ChenNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.
Cheng-Chih HsiaoNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.
Marie-José MeliefMS Center ErasMS, Departments of Neurology and Immunology, Erasmus MC, University Medical Center Rotterdam, 3015 CN Rotterdam, the Netherlands.
Adil HarroudThe Neuro (Montreal Neurological Institute-Hospital), Montréal, QC H3A 2B4, Canada.
Inge HuitingaNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.
Jörg HamannNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.
Joost SmoldersNeuroimmunology Research Group, Netherlands Institute for Neuroscience, 1105 BA Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic variant rs10191329

Indexed as

GeneticsImmunologyNeurology

Identifiers

PMID40352730
PMCPMC12063138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.