Evidence map›Paper›PMID 40352685›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Disentangling the effects of sex and gender on

Tatiana Dessy, Amina Barhdadi, Marie-Christyne Cyr, Johanna Sandoval, Louis Bherer, Joëlle Rouleau, Sylvie Provost, Louis-Philippe Lemieux Perreault, Marie-Pierre Sylvestre, Sarah A Gagliano Taliun and 1 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Sex andInternational journal of molecular sciences · 2025
    Article
  6. Review
  7. Disentangling the effects of sex and gender onAlzheimer's & dementia (Amsterdam, Netherlands)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tatiana DessyMontreal Heart Institute Montreal Quebec Canada.
Amina BarhdadiMontreal Heart Institute Montreal Quebec Canada.
Marie-Christyne CyrMontreal Heart Institute Montreal Quebec Canada.
Johanna SandovalMontreal Heart Institute Montreal Quebec Canada.
Louis BhererMontreal Heart Institute Montreal Quebec Canada.
Joëlle RouleauFaculty of Arts and Sciences Université de Montréal Montréal Quebec Canada.
Sylvie ProvostMontreal Heart Institute Montreal Quebec Canada.
Louis-Philippe Lemieux PerreaultMontreal Heart Institute Montreal Quebec Canada.
Marie-Pierre SylvestreMontreal Heart Institute Montreal Quebec Canada.
Sarah A Gagliano TaliunMontreal Heart Institute Montreal Quebec Canada.
Marie-Pierre DubéMontreal Heart Institute Montreal Quebec Canada.ORCID https://orcid.org/0000-0001-8442-4393

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionThe apolipoprotein E (

methodsBiological sex was inferred from sex chromosomes, and a femininity score (FS) was used as a proxy for gender. We analyzed 276,596 UK Biobank participants without prior NCI to assess whether sex and FS modified the effect of

resultsNCI risk was higher in DISCUSSION: Our findings show that Highlights: Apolipoprotein E (

Indexed as

apolipoprotein Egenderneurocognitive impairmentsex difference

Identifiers

PMID40352685
PMCPMC12064333

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.