ArticleNature photonics2025
Full-field Brillouin microscopy based on an imaging Fourier-transform spectrometer.
Article in Nature photonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Brillouin microscopic assessment of retinal stiffness during reactive Müller gliosis.Experimental eye research · 2026Article
- A framework for spontaneous Brillouin noise: unveiling fundamental limits in Brillouin metrology.Light, science & applications · 2026Article
- Full-field Brillouin microscopy based on an imaging Fourier-transform spectrometer.Nature photonics · 2025Article
- Optical characterization of molecular interaction strength in protein condensates.Molecular biology of the cell · 2024Article
- Optical characterization of molecular interaction strength in protein condensates.bioRxiv : the preprint server for biology · 2024Article
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Authors and funding
2 authors.
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Abstract
Brillouin microscopy is an emerging optical elastography technique that can be used to assess mechanical properties of biological samples in a three-dimensional, all-optical and hence non-contact fashion. However, the low cross-section of spontaneous Brillouin scattering produces weak signals that often necessitate prolonged exposure times or illumination dosages that are potentially harmful for biological samples. Here we present a new approach for highly multiplexed and therefore rapid spectral acquisition of the Brillouin-scattered light. Specifically, by exploiting a custom-built Fourier-transform imaging spectrometer and the symmetric properties of the Brillouin spectrum, we experimentally demonstrate full-field 2D spectral Brillouin imaging of phantoms as well as biological samples, at a throughput of up to 40,000 spectra per second, with a precision of ~70 MHz and an effective 2D image acquisition speed of 0.1 Hz over a ~300 × 300 µm
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Registered trials
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