Evidence map›Paper›PMID 40352464›Full record

ArticleChem2025

Rapid Access to 3-Substituted Bicyclo[1.1.1]pentanes.

Katherine I Burton, David W C MacMillan

Abstract read
In one paragraph

Article in Chem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Harnessing COJournal of the American Chemical Society · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katherine I BurtonMerck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.
David W C MacMillanMerck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, United States.

Funding

Photoredox Catalysis Applications in Organometallics and Chemical BiologyR35GM134897 · NIGMS · PRINCETON UNIVERSITY · PI David W MacMillan · 2020 to 2026
$6.3M
NIGMS NIH HHS R35 GM134897
6 · The paper itself

Abstract

The prevalence of benzene rings in pharmaceutical scaffolds has prompted efforts to identify structural bioisosteres with improved

Indexed as

bicyclo[1.1.1]pentane organobromide activationbioisosterecopper catalysishalogen abstractionphotoredoxreaction modularity

Identifiers

PMID40352464
PMCPMC12061040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.