Evidence map›Paper›PMID 40352452›Full record

ArticleFrontiers in endocrinology2025

Approach to signal loss in intraoperative nerve monitoring in thyroid surgery questionnaire: a Turkish surgical perspective.

Yalin Iscan, Irem Karatas, Nurcihan Aygun, Ahmet Cem Dural, Serkan Teksoz, Ozer Makay, Ali Uğur Emre, Fatih Tunca, Mehmet Uludag, Gökhan İçöz and 3 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yalin IscanDivision of Endocrine Surgery, Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Irem KaratasDepartment of General Surgery, Mardin Training and Research Hospital, Mardin, Türkiye.
Nurcihan AygunDivision of Endocrine Surgery, Department of General Surgery, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Ahmet Cem DuralDepartment of General Surgery, Faculty of Medicine, Istinye University, Istanbul, Türkiye.
Serkan TeksozDivision of Endocrine Surgery, Department of General Surgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Ozer MakayDepartment of General Surgery, Ozel Saglik Hospital, Izmir, Türkiye.
Ali Uğur EmreDepartmant of General Surgery, Anadolu Medical Center Hospital, Istanbul, Türkiye.
Fatih TuncaDivision of Endocrine Surgery, Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Mehmet UludagDivision of Endocrine Surgery, Department of General Surgery, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Gökhan İçözDivision of Endocrine Surgery, Department of General Surgery, Ege University Hospital, Izmir, Türkiye.
Yasemin Giles SenyürekDivision of Endocrine Surgery, Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Adnan IşgörDepartment of General Surgery, Sisli Memorial Hospital, Istanbul, Türkiye.
Mehmet HaciyanliDepartmant of General Surgery, Izmir Katip Celebi University, Atatürk Training And Research Hospital, Izmir, Türkiye.

Funding

Graduate Training at the Interface of Neuroscience, Optical Engineering and Data ScienceT32NS136080 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI David A Boas, Jerry L Chen · 2024 to 2026
$661k
NINDS NIH HHS T32 NS136080
6 · The paper itself

Abstract

Purpose: This study aimed to evaluate surgeons' use of intraoperative nerve monitoring (IONM) during thyroidectomy and their approach to loss of signal (LOS) in various clinical scenarios. Materials and Methods: A survey was conducted by the Turkish Endocrine Surgery Society on members of the Society in February 2020 and consisted of 16 questions. The practice of IONM use, rate of inclusion in informed consent texts, and attitudes of participants in case of signal loss were investigated. The study was conducted with 183 participants between February 4-12, 2020. Results: Most participants (58.2%) had more than 10 years of surgical experience and 36.6% performed more than 50 thyroidectomies annually. IONM was routinely used by 78.7% of the participants, whereas 16.4% reserved its use in difficult cases. Only 5.2% of the participants performed continuous monitoring. In case-based LOS scenarios, the majority of participants (approximately 60%) terminated the operation when the nerve was anatomically intact but LOS persisted, except in high-risk cancer cases. When the nerve anatomy was disrupted, most participants terminated the surgery, except for the high-risk cancer group. In cases of irreversible LOS with preserved nerve integrity, 58.9% of the patients preferred continuous vagus stimulation on the contralateral side, whereas 41.1% preferred intermittent nerve monitoring. Although 68.2% of the participants verbally informed the patients about the risks of LOS, only 24.4% provided this information on the consent form. Conclusion: The use of IONM in thyroid surgery is increasing in our country. However, there is still no consensus on the approach for staged thyroidectomy in cases of signal loss, and institutional and individual differences persist. Further studies are needed to determine the medical-legal implications and effects of these variations.

Indexed as

Intraoperative Neurophysiological MonitoringMonitoring, IntraoperativeThyroidectomyThyroid GlandAdultFemaleHumansMaleMiddle AgedSurveys and QuestionnairesTurkeyintraoperative nerve monitoring (IONM)loss of signal (LOS)recurrent laryngeal nervestaged thyroidectomythyroid surgerytotal thyroidectomy

Identifiers

PMID40352452
PMCPMC12061687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.