Evidence map›Paper›PMID 40352337›Full record

ArticleSaudi journal of medicine & medical sciences

Prevalence of Exocrine Pancreatic Insufficiency in Patients with Chronic Diarrhea.

Tara Keihanian, Suneal Agarwal, Nabil Mansour, Michael Mercado, Hashem B El-Serag, Mohamed O Othman

Abstract read
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In one paragraph

Article in Saudi journal of medicine & medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tara KeihanianDepartment of Medicine, Division of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.
Suneal AgarwalDepartment of Medicine, Division of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.
Nabil MansourDepartment of Medicine, Division of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.
Michael MercadoDepartment of Medicine, Division of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.
Hashem B El-SeragDepartment of Medicine, Division of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.
Mohamed O OthmanDepartment of Medicine, Division of Gastroenterology, Baylor College of Medicine, Houston, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Exocrine pancreatic insufficiency (EPI) is an underdiagnosed entity among patients with new-onset chronic diarrhea (CD). The aim of this study is to investigate the prevalence of EPI in patients with CD. Materials and Methods: Patients with new-onset CD (≥4 weeks) from 2018 to 2021 were enrolled in this single-center prospective study. If stool fecal elastase (FE) was <200 μg/g, patients were offered a confirmatory 72-hour fecal fat test. Results: FE testing was completed by 97 patients, of which 9 had low FE (9.3%). Average weight was significantly higher in patients with low FE (98.5 ± 29.3 kg vs 82.2 ± 22.2 kg; Conclusion: Considering the 9.3% prevalence of EPI among patients with CD, we propose screening for EPI with stool FE as part of the initial workup for these patients.

Indexed as

Chronic diarrheaexocrine pancreatic insufficiencyfecal elastasepancreatic enzyme replacement therapypancreatic parenchymal changes

Identifiers

PMID40352337
PMCPMC12063964

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.