ArticleRheumatology advances in practice2025
A psychometric evaluation of the Musculoskeletal Health Questionnaire (MSK-HQ): validation and measurement invariance in inflammatory arthritis.
Article in Rheumatology advances in practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: The Musculoskeletal Health Questionnaire (MSK-HQ) is a patient reported outcome measure (PROM) co-produced for use across musculoskeletal diseases. This study analyses the validity, reliability, sensitivity to change and measurement invariance of the MSK-HQ in inflammatory arthritis (IA). Methods: A total of 5106 patients recruited to the National Early Inflammatory Arthritis Audit (NEIAA) between May 2018 and March 2020 with a diagnosis of IA were included. Patients completed PROMs at baseline and 3 and 12 months alongside clinic visits. Convergent validity was assessed in relation to the HAQ-II, Patient Health Questionnaire 4 (PHQ-4) and 28-item DAS (DAS28). Construct validity was assessed using confirmatory factor analysis (CFA). Hierarchical tests for configural, metric and scalar invariance determined measurement invariance in item CFAs. Results: The MSK-HQ total score correlated well with the HAQ-II ( Conclusion: This study provides evidence for the validity and sensitivity to change of the MSK-HQ in patients with IA, with a change of >4 points likely to be clinically meaningful. The MSK-HQ has high convergent and construct validity and is sensitive to change, providing a valuable tool for clinical care and research studies.
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