Evidence map›Paper›PMID 40352260›Full record

ArticleFrontiers in nutrition2025

Investigating nutrient intake during use of glucagon-like peptide-1 receptor agonist: a cross-sectional study.

Brittany Johnson, Mary Milstead, Olena Thomas, Tyler McGlasson, Lauren Green, Rachel Kreider, Rachel Jones

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brittany JohnsonGNC Holdings, LLC, Pittsburgh, PA, United States.
Mary MilsteadGNC Holdings, LLC, Pittsburgh, PA, United States.
Olena ThomasGNC Holdings, LLC, Pittsburgh, PA, United States.
Tyler McGlassonGNC Holdings, LLC, Pittsburgh, PA, United States.
Lauren GreenGNC Holdings, LLC, Pittsburgh, PA, United States.
Rachel KreiderGNC Holdings, LLC, Pittsburgh, PA, United States.
Rachel JonesGNC Holdings, LLC, Pittsburgh, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glucagon-like peptide-1 receptor agonist (GLP-1RA) pharmaceutical interventions have advanced medical treatment for obesity, yet little is known about nutrient intake while using a GLP-1RA. The purpose of this study was to compare nutrient intake while using a GLP-1RA to the Dietary Reference Intakes (DRI). Methods: A cross-sectional study was conducted in a sample of participants who had been using GLP-1RA for at least one month ( Results: Compared to the DRI reference values, participants consumed adequate amounts of B-vitamins, copper, phosphorus, selenium, and zinc. Participants had insufficient intakes of several key nutrients below the DRI, including fiber (14.5 g; CI: 12-17), calcium (863 mg; CI: 756-970), iron (12.1 mg; CI: 11-13), magnesium (266 mg; CI: 236-297), potassium (2,186 mg; CI: 1,969-2,402), choline (305 mg; CI: 268-342), vitamin A (560 mcg RAE; CI: 469-651), vitamin C (51 mg; CI: 41-61), vitamin D (4 mcg; CI: 3-5), vitamin E (9.6 mg; CI: 8-11), and Conclusion: Participants on a GLP-1RA are not meeting the DRI for several vital nutrients through their diet or higher protein needs during weight loss. Patient-centered nutritional guidance is essential to optimize health outcomes and prevent unintended health consequences. Future large-scale studies are needed to assess the replicability of these findings and provide custom nutritional guidance for those on a GLP-1RA medication.

Indexed as

dietdietary reference intakesglucagon-like peptide-1 receptor agonistsnutrient intakenutritionweight loss

Identifiers

PMID40352260
PMCPMC12062175

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.