ArticleFrontiers in physiology2025
Characteristics and hemolysis analysis of centrifugal blood pumps under different speed modulations.
Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Trial-Based Hemolysis Modeling to Investigate Operating Modes of Continuous-Flow LVADs.Artificial organs · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Constant-speed methods are widely applied and studied in rotary blood pumps. However, various speed modulation which have been used in commercial blood pump lacks validation of the ventricular assist capability and hemolysis potential. Methods: This study investigates the hydrodynamic performance and hemolysis of a rotary ventricular assist device under sinusoidal speed modulation, focusing on the combined effects of phase, baseline speed, and speed fluctuation amplitude. Results: Computational fluid dynamics (CFD) coupled with a dynamic cardiovascular model revealed that counter-phase modulation reduces hemolysis index (HI) fluctuations compared to in-phase conditions, while higher baseline speeds increase time-averaged HI due to prolonged exposure to non-physiological shear stress. Larger amplitudes expand the operational range but exacerbate HI variability. Discussion: These findings demonstrate that phase synchronization critically balances pulsatility and hemocompatibility, providing actionable insights for adaptive speed control strategies in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.