Evidence map›Paper›PMID 40352019›Full record

ArticleCureus2025

High-Dose Corticosteroid Therapy in Facial Nerve Palsy: A Retrospective Study.

Hiroshi Hyakusoku, Noriyuki Katsumata, Meijin Nakayama

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hiroshi HyakusokuOtorhinolaryngology, Yokosuka Kyosai Hospital, Yokosuka, JPN.
Noriyuki KatsumataOtorhinolaryngology, Yokosuka Kyosai Hospital, Yokosuka, JPN.
Meijin NakayamaOtorhinolaryngology, Yokosuka Kyosai Hospital, Yokosuka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives The difference in therapeutic efficacy between an initial dosage of 200 mg and 100 mg prednisolone (PSL) with a taper for Bell's palsy and Ramsay Hunt syndrome was retrospectively investigated. Methods A total of 259 patients (172 with Bell's palsy and 87 with Ramsay Hunt syndrome) were treated with high-dose corticosteroid therapy (HDCT) with PSL (the standard HDCT: 200 mg/day for three days with a seven-day taper, or the reduced HDCT: 100 mg/day for three days with a seven-day taper) and evaluated once a month by the Yanagihara facial nerve grading system until facial nerve paralysis was cured or six months after the onset. Results The therapeutic efficacy of the standard HDCT was not significantly improved, compared to the reduced HDCT, in Bell's palsy and Ramsay Hunt syndrome, and even in less than 20.0% of electroneuronography in Bell's palsy and Ramsay Hunt syndrome. Conclusion HDCT with more than an initial dosage of 100 mg/day PSL with a taper for Bell's palsy and Ramsay Hunt syndrome does not increase the therapeutic efficacy.

Indexed as

bell’s palsyfacial nerve paralysishigh-dose corticosteroid therapyprednisoloneramsay hunt syndrome

Identifiers

PMID40352019
PMCPMC12063513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.