ReviewCureus2025
Regional Nerve Blocks for Trauma Pain in the Emergency Department: A Systematic Review of Efficacy and Safety.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective acute pain management in the emergency department is essential, especially for patients with fractures, dislocations, and other musculoskeletal injuries. Conventional approaches like systemic opioids and procedural sedation, while commonly used, can lead to side effects such as respiratory issues, nausea, extended emergency department stays, and potential opioid dependence. In recent years, ultrasound-guided nerve blocks have gained attention as a safer and more targeted method of pain control that can reduce reliance on opioids. This review explored how ultrasound-guided nerve blocks compare to traditional pain management strategies in terms of effectiveness, safety, and clinical outcomes. A detailed search was conducted across several major medical databases, including PubMed, Scopus, Web of Science, the Cochrane Central Register of Controlled Trials, and the Virtual Health Library. Search terms focused on ultrasound, anesthesia, nerve blocks, and emergency care. The review included only randomized controlled trials published in English that involved adult patients receiving ultrasound-guided nerve blocks for acute pain in emergency settings. The main outcomes assessed were pain relief (measured using validated scales), opioid use, time spent in the emergency department, patient satisfaction, and adverse events. Out of 3,299 studies initially identified, 2,430 remained after removing duplicates. After reviewing 60 full-text articles, nine met the inclusion criteria for analysis. The results showed that ultrasound-guided nerve blocks provided more rapid and sustained pain relief than standard treatments, with a noticeable reduction in opioid use. They were also linked to shorter emergency department stays, higher levels of patient satisfaction, and a low rate of complications when carried out by trained providers. These findings suggest that ultrasound-guided nerve blocks can be a highly effective first-line option for managing acute pain in trauma patients. Still, further studies are recommended to optimize their use and encourage broader implementation in emergency care settings.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.