Evidence map›Paper›PMID 40351973›Full record

ArticleCureus2025

Postoperative Neurological Deficits Following Regional Anesthesia: A Rare Case of Transient Aphasia and Hemiparesis.

Regina McPherson, Juan Ramon Santos Rivera, Christine Zickler, Guillermo Izquierdo-Pretel

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Regina McPhersonInternal Medicine, Florida International University, Florida, USA.
Juan Ramon Santos RiveraInternal Medicine, Ponce Health Sciences University, Ponce, PRI.
Christine ZicklerMedicine, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Guillermo Izquierdo-PretelHospital Medicine, Jackson Memorial Hospital, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological impairments after anesthesia are fairly common and can oftentimes be serious. A thorough patient evaluation is imperative to discriminate between impairments related to the anesthesia itself and more serious, unrelated complications. Transient motor deficits, aphasia, and postoperative delirium have been reported after general anesthesia and can be related to perioperative stress, exacerbation of previous undiagnosed neurological disorders, and the under-reported psycho-emotional effects of undergoing anesthesia. We present the case of a 57-year-old female who developed expressive aphasia and right-sided weakness following elective ankle arthrodesis performed under monitored anesthesia care (MAC) with regional anesthesia. Medical history was significant for type 2 diabetes mellitus (T2DM), hypertension (HTN), chronic kidney disease (CKD), and Charcot joint. Her presentation sparked initial concern for a cerebrovascular event; however, imaging ruled out stroke and large vessel occlusion. Her neurological deficits were attributed to a rare and under-reported anesthesia-related complication: the psycho-emotional effects of regional anesthesia. The patient demonstrated a gradual recovery of speech and motor function without additional interventions and required inpatient rehabilitation to regain functional independence. This case highlights the importance of prompt evaluation of postoperative neurological symptoms, particularly in patients with significant comorbidities, and underscores the need for increased awareness of rare complications associated with anesthesia.

Indexed as

neurological effects of regional anesthesiapost anesthesia aphasiapost anesthesia hemiparesisregional anesthesia and chronic paintransient aphasia

Identifiers

PMID40351973
PMCPMC12063510

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.