ArticleCureus2025
Severity of Pain at Admission and Development of Symptoms of Anxiety and Depression: A Study of Burn Patients at a Tertiary Healthcare Facility in Ghana.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background Burns remain a global public health concern and one of the major causes of painful injury, which impacts patients physically and psychologically. Pain causes more suffering in the acute stage and rehabilitation in burn patients, which is associated with anxiety, depression, and post-traumatic stress disorder that can lead to long-term consequences, which negatively affects the quality of life (QoL) of the patient. Objective This study aimed to determine the influence of the severity of pain at admission on the development of symptoms of anxiety and depression among burn patients within the first week of admission. Methods An analytical cross-sectional study was conducted among adult burn patients at the Burns Centre of the Korle-Bu Teaching Hospital. Patients' demographic and clinical characteristics, such as age, cause of burns, degree of burns, and percentage of total body surface area (TBSA), were recorded. Hospital Anxiety and depression scale (HADS) was used to assess anxiety and depression symptoms, while the Visual Analog Scale (VAS) was used to evaluate the intensity of pain. Simple linear regression was used to determine the influence of the severity of pain at admission on symptoms of anxiety and depression. Results Sixty-five adult inpatients were enrolled, with a mean age of 35.9 years. About 92% presented with severe pain, and two-thirds developed severe anxiety (66.2%) or depressive (67.7%) symptoms. The mean (±SD) anxiety symptoms, depression symptoms, and pain scores were 11.4(±2.7), 11.8(±3.4), and 8.5(±1.6), respectively. Mean anxiety symptom scores were significantly different between the age groups, %TBSA, and severity of pain. Mean depression symptom scores were significantly different between the severity of pain and the cause of burn injury. There was a significant positive relationship between the severity of pain on admission and the level of depression and anxiety symptoms. Conclusion Patients with burn injury present with severe pain at admission, and the majority develop significant anxiety and depressive symptoms within the first week of admission. The intensity of pain at admission is significantly associated with the level of anxiety and depression.
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