ArticleCureus2025
Systemic Involvement of Leukocytoclastic Vasculitis in Skin of Color.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leukocytoclastic vasculitis (LCV) is an immune-mediated small-vessel vasculitis with various underlying causes. We present a unique case of LCV in an elderly man with Fitzpatrick phototype V skin to highlight multi-organ signs associated with this rare pathology. Our patient presented with an evolving, diffusely spread rash following respiratory symptoms accompanied by muscle weakness, scant hemoptysis, and decreased visual acuity. A comprehensive diagnostic approach, including skin biopsy, revealed LCV with associated eosinophilia. Treatment through a multidisciplinary approach included systemic steroids, topical ointments, and empiric antibiotics. The patient showed gradual improvement and was discharged after nine days of hospitalization. Differential diagnoses for the rash included infections, inflammatory processes, and autoimmune vasculitides such as immunoglobulin A (IgA) vasculitis, urticarial vasculitis, cryoglobulinemic vasculitis, and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. While most instances of LCV are typically skin-limited and self-resolving, this case highlights diffuse systemic involvement requiring a broad diagnostic perspective.
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