Evidence map›Paper›PMID 40351892›Full record

ArticleCureus2025

A Rare Case of Primary Hyperaldosteronism Resulting in Severe Hypokalemia.

Saad Sameer, Aya J Qassim, Ali Aqel, Yousef H Al-Asa'd, Shaefiq Babu Thappy

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saad SameerInternal Medicine, Hamad General Hospital, Doha, QAT.
Aya J QassimInternal Medicine, Hamad General Hospital, Doha, QAT.
Ali AqelInternal Medicine, Hamad General Hospital, Doha, QAT.
Yousef H Al-Asa'dInternal Medicine, Hamad General Hospital, Doha, QAT.
Shaefiq Babu ThappyNephrology, Hamad General Hospital, Doha, QAT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperaldosteronism often clinically manifests as hypertension with mild to moderate hypokalemia. However, in rare cases, it can also present primarily with severe hypokalemia. In this case report, we will be discussing our patient, a 43-year-old woman who presented with abdominal cramps and vomiting, along with severe muscle cramps resulting in an inability to walk. She was found to have an undetectable level of serum potassium and prolonged QT interval on her ECG. After aggressive electrolyte correction and further imaging and endocrinology studies, she was diagnosed to have primary hyperaldosteronism. She was appropriately referred for urgent outpatient adrenalectomy, which turned out to be curative. Our case highlights the importance of timely diagnosis, interventions, and multidisciplinary care for patients with primary hyperaldosteronism.

Indexed as

adrenal adenomaendocrinologyhypokalemia related medical emergenciesmulti-disciplinary carenephrologyprimary hyperaldosteronismrobotic adrenalectomy

Identifiers

PMID40351892
PMCPMC12066027

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.