Evidence map›Paper›PMID 40351819›Full record

ArticleJournal of metabolic and bariatric surgery2025

Bariatric Surgery Reduces Lipid Profile and Oxidative Stress in Patients With Obesity: A Prospective Cohort Study.

Gabriela de Souza Bett, Fabiana Schuelter-Trevisol, Ricardo Reis do Nascimento, Bruna Barros Fernandes, Larissa Espindola da Silva, Mariella Reinol da Silva, Jefferson Luiz Traebert, Eliane da Silva Azevedo Traebert, Gislaine Tezza Rezin, Daisson José Trevisol

Abstract read
In one paragraph

Article in Journal of metabolic and bariatric surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriela de Souza BettPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Fabiana Schuelter-TrevisolPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Ricardo Reis do NascimentoCurso de Medicina, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Bruna Barros FernandesPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Larissa Espindola da SilvaPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Mariella Reinol da SilvaPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Jefferson Luiz TraebertPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Eliane da Silva Azevedo TraebertPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Gislaine Tezza RezinPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.
Daisson José TrevisolPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Sul de Santa Catarina (UNISUL), Tubarão, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate inflammatory and biochemical parameters in the serum of patients with obesity before and after bariatric surgery. Materials and Methods: An epidemiological study of the prospective cohort type was conducted to follow patients classified with grade II or III obesity undergoing bariatric surgery. Body mass index (BMI), lipid profile, C-reactive protein (CRP), reactive oxygen species production using dichlorofluorescein (DCF), and antioxidant defenses superoxide dismutase (SOD) and reduced glutathione (GSH) were analyzed before and 3 months after Roux-en-Y bariatric surgery. Results: A paired analysis was conducted, evaluating 23 patients in the pre- and post-surgical period. A statistically significant reduction was observed after bariatric surgery in BMI (P value<0.001), total cholesterol (CT) (P value=0.0006), total triglycerides (P value=0.0025), high-density lipoprotein cholesterol (P value=0.0010), low-density lipoprotein cholesterol (P value=0.0189), CRP (P value=0.0130), DCF (P value=0.0069), and GSH (P value<0.0001), as well as an increase in SOD activity (P value=0.0005). Conclusion: Bariatric surgery effectively reduced inflammatory and lipid markers and reversed oxidative stress, indicating that the procedure improves the health of bariatric patients across various parameters.

Indexed as

Bariatric surgeryInflammation mediatorsLipoproteinsObesityOxidative stress

Identifiers

PMID40351819
PMCPMC12059305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.