Evidence map›Paper›PMID 40351693›Full record

SynthesisReviews in cardiovascular medicine2025

Artificial Intelligence-Assisted Echocardiographic Image-Analysis for the Diagnosis of Fetal Congenital Heart Disease: A Systematic Review and Meta-Analysis.

Yaduan Gan, Lin Yang, Jianmei Liao

Abstract readSystematic Review
In one paragraph

Synthesis in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yaduan GanDepartment of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, 363000 Zhangzhou, Fujian, China.ORCID https://orcid.org/0009-0002-8272-643X
Lin YangDepartment of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, 363000 Zhangzhou, Fujian, China.ORCID https://orcid.org/0000-0002-6712-4345
Jianmei LiaoDepartment of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, 363000 Zhangzhou, Fujian, China.ORCID https://orcid.org/0000-0003-2377-0799

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To assess the precision of artificial intelligence (AI) in aiding the diagnostic process of congenital heart disease (CHD). Methods: PubMed, Embase, Cochrane, and Web of Science databases were searched for clinical studies published in English up to March 2024. Studies using AI-assisted ultrasound for diagnosing CHD were included. To evaluate the quality of the studies included in the analysis, the Quality Assessment Tool for Diagnostic Accuracy Studies-2 scale was employed. The overall accuracy of AI-assisted imaging in the diagnosis of CHD was determined using Stata15.0 software. Subgroup analyses were conducted based on region and model architecture. Results: The analysis encompassed a total of 7 studies, yielding 19 datasets. The combined sensitivity was 0.93 (95% confidence interval (CI): 0.88-0.96), and the specificity was 0.93 (95% CI: 0.88-0.96). The positive likelihood ratio was calculated as 13.0 (95% CI: 7.7-21.9), and the negative likelihood ratio was 0.08 (95% CI: 0.04-0.13). The diagnostic odds ratio was 171 (95% CI: 62-472). The summary receiver operating characteristic (SROC) curve analysis revealed an area under the curve of 0.98 (95% CI: 0.96-0.99). Subgroup analysis found that the ResNet and DenNet architecture models had better diagnostic performance than other models. Conclusions: AI demonstrates considerable value in aiding the diagnostic process of CHD. However, further prospective studies are required to establish its utility in real-world clinical practice. The PROSPERO registration: CRD42024540525, https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=540525.

Indexed as

artificial intelligencecongenital heart diseasediagnostic accuracyfetal echocardiographymeta-analysis

Identifiers

PMID40351693
PMCPMC12059730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.