Evidence map›Paper›PMID 40351683›Full record

ReviewReviews in cardiovascular medicine2025

Structural Heart Interventions in Patients with Left Ventricular Assist Devices.

Puvi Seshiah, Eugene Chung, Santiago Garcia, Joseph Choo, Robert Dowling, Geoffrey Answini, Dean Kereiakes, Gregory Egnaczyk

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Puvi SeshiahThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0009-0007-3192-3878
Eugene ChungThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0000-0002-9443-3274
Santiago GarciaThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0000-0002-1806-6783
Joseph ChooDepartment of Cardiology, Charleston Area Medical Center/Vandalia Health, Charleston, WV 25304, USA.ORCID https://orcid.org/0009-0009-8973-5145
Robert DowlingThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0009-0005-4285-7875
Geoffrey AnswiniThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0009-0009-9344-8667
Dean KereiakesThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0000-0003-1086-127X
Gregory EgnaczykThe Christ Hospital Heath Network, The Heart & Vascular Institute, Cincinnati, OH 45219, USA.ORCID https://orcid.org/0000-0002-1909-2334

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular assist devices (LVADs) have changed the landscape for patients with advanced heart failure (HF). With advances in pump design and management, patients with LVADs are living longer with improved quality of life despite having more comorbidities and complex structural heart disease. As such, HF cardiologists and surgeons collaborate more frequently with structural heart interventionalists to address the complex problems of patients with LVADs who present at different points of failure in their circuits. Unlike heart transplants and total artificial heart recipients, the native heart and its components must function to maintain successful circulatory support from these assist devices. Multiple points of potential failure of the native heart and the LVAD circuit exist that can result in significant morbidity and mortality. These include regurgitant valve lesions, interatrial shunts, outflow cannula obstruction, and pump thrombosis. Transcatheter interventions can be applied and tailored specifically to the anatomy of the individual in these situations to improve the lives and outcomes of our LVAD patients. This review provides a comprehensive approach for diagnosing and treating structural heart disease associated with patients who have LVADs, focusing on multidisciplinary collaboration and individualized interventional strategies.

Indexed as

left ventricular assist devicetranscatheter interventionsvalvular heart disease

Identifiers

PMID40351683
PMCPMC12059792

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.