Evidence map›Paper›PMID 40351682›Full record

SynthesisReviews in cardiovascular medicine2025

Myocarditis in Hypertrophic Cardiomyopathy: Incidence and Contribution to Disease Progression and Outcome.

Yulia Lutokhina, Nasiba Seifatova, Polina Chernova, Natalia Kireeva, Roman Komarov, Marina Vukolova, Sergey Pirozhkov, Ekaterina Yantikova, Nargiza Babakulova, Boris Tlisov and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yulia LutokhinaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-7154-6794
Nasiba SeifatovaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0009-0003-5588-4923
Polina ChernovaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0009-0000-3468-9115
Natalia KireevaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-3467-886X
Roman KomarovMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-3904-6415
Marina VukolovaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-9046-169X
Sergey PirozhkovMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-7116-3398
Ekaterina YantikovaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0009-0001-7739-9633
Nargiza BabakulovaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0002-8740-9575
Boris TlisovMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0003-4094-8771
Andrey DzyundzyaMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0003-1133-8106
Beatrice VolelMoscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), 119991 Moscow, Russian Federation.ORCID https://orcid.org/0000-0003-1667-5355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myocardial diseases such as myocarditis and cardiomyopathies are clinically important and can cause complications such as heart failure and arrhythmias, which increase the risk of death. The combination of myocarditis with cardiomyopathy is difficult to diagnose because their manifestations often overlap, and multiple myocardial diseases are usually not included in the diagnostic search. Hypertrophic cardiomyopathy (HCM) is the most common cardiomyopathy; however, few studies have examined the combination of myocarditis and HCM, thereby highlighting the importance of this problem. This article aimed to analyze the influence of myocarditis on clinical features and outcomes in patients with HCM. Methods: A literature search was performed using PubMed and the Scientific Electronic Library eLIBRARY.ru databases. Relevant studies, published until November 2023, were analyzed in detail. Studies were selected in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards. Results: Twelve studies (three original articles and nine clinical cases) were isolated from a total cohort of 1504 publications and were included in the study. The prevalence of myocarditis in HCM ranged from 23.5% to 46.7%. The presence of concomitant myocarditis in patients with HCM was associated with heart failure progression, worsening of ventricular arrhythmias, and an increased risk of sudden cardiac death. Conclusions: The incidence of myocarditis in HCM is high. Early detection and treatment of myocarditis in patients with HCM can slow the progression of heart failure rhythm disturbances and improve the disease prognosis. The PROSPERO Registration: The systematic review was registered in the International Prospective Register of Systematic Reviews PROSPERO (CRD42024499672, https://www.crd.york.ac.uk/PROSPERO/view/CRD42024499672).

Indexed as

HCMhypertrophic cardiomyopathyimmunosuppressive therapyinflammatory cardiomyopathymyocardial biopsymyocarditisprimary myocardial hypertrophy

Identifiers

PMID40351682
PMCPMC12059768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.