Evidence map›Paper›PMID 40351565›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2025

Dyskinesia-Hyperpyrexia Syndrome in Parkinson's Disease May Benefit from GPi Deep Brain Stimulation: A Case Report.

Shi-Shi Huang, Lu-Lu Ma, Han-Song Sheng, Rong-Pei Liu, Shi-Guo Zhu, Shan-Shan Xu, Mei-Ling Sheng, Zhu-Ling Chen, Nu Zhang, Xiong Zhang and 1 more

Abstract readCase Reports
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shi-Shi Huang *Department of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0000-0001-5886-3341
Lu-Lu Ma *Department of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Han-Song Sheng *Department of Neurosurgery, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Rong-Pei LiuDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Shi-Guo ZhuDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0000-0002-3439-2319
Shan-Shan XuDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0009-0003-8439-7382
Mei-Ling ShengDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhu-Ling ChenDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Nu ZhangDepartment of Neurosurgery, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Xiong ZhangDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0000-0002-5686-0953
Jian-Yong WangDepartment of Neurology, Institute of Geriatric Neurology, the Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.ORCID 0000-0003-4695-4806

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dyskinesia-hyperpyrexia syndrome (DHS) is a rare but life-threatening complication in Parkinson's disease (PD). Its prevention and treatment are clinical challenges. Case report: We herein present a case of a female PD patient who experienced recurrent episodes of DHS and levodopa-induced dyskinesia. The complications were alleviated after bilateral globus pallidus internus (GPi) deep brain stimulation (DBS). Discussion: Our report provides evidence that GPi DBS may reduce the susceptibility to DHS. More evidences are warranted to validate this hypothesis.

Indexed as

Deep Brain StimulationDyskinesia, Drug-InducedFeverGlobus PallidusParkinson DiseaseAgedAntiparkinson AgentsFemaleHumansLevodopaSyndromeAntiparkinson AgentsLevodopaDeep brain stimulationDyskinesiaDyskinesia-hyperpyrexia syndromeGlobus pallidus internusParkinson’s disease

Identifiers

PMID40351565
PMCPMC12063572

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.