Evidence map›Paper›PMID 40351536›Full record

ArticleDose-response : a publication of International Hormesis Society

Effect of Gamma Rays on Adropin as a Potential Hepatokine Marker for Liver Damage in Male Albino Rats.

Nadia Abdel-Magied, Amira Mk Abouelella, Hayam Mostafa, Hebatallah E Mohamed, Nehal I Hendy

Abstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadia Abdel-MagiedDepartment of Radiation Biology Research, National Centre for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Egypt, Cairo.ORCID https://orcid.org/0000-0002-9726-762X
Amira Mk AbouelellaDepartment of Radiation Biology Research, National Centre for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Egypt, Cairo.
Hayam MostafaDepartment of Radiation Biology Research, National Centre for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Egypt, Cairo.
Hebatallah E MohamedDepartment of Radiation Biology Research, National Centre for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Egypt, Cairo.
Nehal I HendyHuman Physiology Department, Faculty of Human Medicine, Zagazig University, Egypt, Zagazig.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This work was the first study to show the impact of γ- radiation on adropin levels in the serum and liver tissue of male albino rats. Methods: Liver tissue and blood samples of rats were collected at 1, 3, 7 and 14 days after whole-body exposure to 7.5 Gy of γ-radiation. Results: Irradiated groups revealed a marked decrease in adropin associated with a significant increase in STAT3 in the serum and gene expression. Furthermore, Conclusion and future scope of work: γ- radiation has adverse effects on adropin that related inversely with STAT3, leading to further damage to liver cells as well as disturbances in lipid and glucose metabolism. Therefore, adropin could be used in people exposed to radiation such radiotherapy to control the serious effects of radiation. Further study is needed to confirm these results.

Indexed as

adropinlipidliverratsSTAT3γ- radiation

Identifiers

PMID40351536
PMCPMC12065993

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.