Evidence map›Paper›PMID 40351527›Full record

ArticleFrontiers in chemistry2025

Chemical profile of

Lena Łyko, Renata Nowak, Marta Olech, Urszula Gawlik, Agnieszka Krajewska, Danuta Kalemba, Andriy Prokopiv

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lena ŁykoDepartment of Pharmaceutical Botany, Medical University of Lublin, Lublin, Poland.
Renata NowakDepartment of Pharmaceutical Botany, Medical University of Lublin, Lublin, Poland.
Marta OlechDepartment of Pharmaceutical Botany, Medical University of Lublin, Lublin, Poland.
Urszula GawlikDepartment of Biochemistry and Food Chemistry, University of Life Sciences, Lublin, Poland.
Agnieszka KrajewskaInstitute of Natural Products and Cosmetics, Lodz University of Technology, Łódź, Poland.
Danuta KalembaInstitute of Natural Products and Cosmetics, Lodz University of Technology, Łódź, Poland.
Andriy ProkopivDepartment of Botany, Botanical Garden, Ivan Franko National University of Lviv, Lviv, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Terpenes are a diverse class of natural metabolites that exhibit a range of biological activities, including antidiabetic, antiproliferative, and anti-inflammatory effects. The present study was designed to determine the chemical profile and biological activity of Materials and methods: The LC-APCI-MS/MS method was used to determine the composition and content of the triterpenes (including sterols). In turn, LC-ESI-MS/MS was applied for the analysis of polyphenolic compounds. The volatile composition of RLL extracts was analysed using the HS-SPME-GC-FID-MS technique. The inhibitory activity against enzymes such as xanthine oxidase (XO), lipoxygenase (LOX), hyaluronidase, α-amylase, and α-glucosidase was assessed using Results and discussion: The LC-MS analyses revealed high levels of oleanolic acid, ursolic acid, and β-sitosterol, which belong to terpenes, as well as polyphenols such as syringic acid, ferulic acid, and p-coumaric acid, along with apigenin and its 7-glucoside. Among volatiles, the most prominent were limonene, eugenol, β-phenylethanol, and β-caryophyllene.

Indexed as

antidiabeticantiinflammatoryflavonoidsLC-MSRhododendron luteumSFEterpenesβ-sitosterol

Identifiers

PMID40351527
PMCPMC12062060

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.