Evidence map›Paper›PMID 40351384›Full record

ArticleBrain communications2025

Reference range for serum neurofilament light chain: findings from healthy Thai adults.

Nontapat Sukhonpanich, Tatchaporn Ongphichetmetha, Ekdanai Uawithya, Jiraporn Jitprapaikulsan, Natthapon Rattanathamsakul, Naraporn Prayoonwiwat, Sasitorn Siritho

Abstract read
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In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nontapat SukhonpanichDivision of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Tatchaporn OngphichetmethaDivision of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.ORCID https://orcid.org/0000-0002-9063-2575
Ekdanai UawithyaSiriraj Neuroimmunology Centre, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Jiraporn JitprapaikulsanDivision of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Natthapon RattanathamsakulDivision of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Naraporn PrayoonwiwatDivision of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Sasitorn SirithoDivision of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum neurofilament light chain is a notable biomarker for detecting axonal injury and has shown significant potential for clinical applications. Establishing a reference interval and cut-off level is a critical step towards implementing a serum neurofilament light chain in routine clinical practice. In this study, we aimed to establish a reference range of serum neurofilament light chains for the Thai population. Blood samples were collected from healthy Thai adults without a history of neurological diseases and screened at the Siriraj Hospital. The relationship between age, sex and log

Indexed as

biomarkerneurofilament light chainreference range

Identifiers

PMID40351384
PMCPMC12062521

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.