ArticleInternational journal of methods in psychiatric research2025
A Ten-Year Cohort Study on the Stability and Trajectories of Psychiatric Diagnosis in Adolescents and Young Adults in Lazio, Italy.
Article in International journal of methods in psychiatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionWe aimed to evaluate the diagnostic stability of a large spectrum of psychiatric diagnoses in adolescents and young adult patients attending specialised facilities in the Lazio Region (Italy).
methodsA total of 3871 subjects (11-35 years) at their first hospitalisation with a psychiatric diagnosis were selected and followed up for 10 years on subsequent hospital admissions to psychiatric care.
resultsA total of 1145 patients were readmitted to a hospital for a psychiatric disorder in the following 10 years. Among these subjects, the concordance between the first and last diagnosis was 57.8% with a weighted kappa of 0.47 (95% CI: 0.42-0.51); the repeated stability (the same diagnosis in at least 75% of admissions) was 31.2%. The diagnostic categories with the highest values of prospective concordance and kappa were schizophrenia spectrum and other functional psychoses (70%, kappa 0.53), substance use disorders (54%, kappa 0.57), and eating disorders (80.9%, kappa 0.76).
conclusionsIn a population study, the stability over time of the first psychiatric diagnosis in a hospital varied according to the specific diagnostic categories, and overall, it was lower than previously reported. The trajectories were disorder-specific, and the stability was influenced by several factors, including the individuals' characteristics, the disorder's severity, and the diagnostic setting.
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