Evidence map›Paper›PMID 40351131›Full record

ArticleFuture oncology (London, England)2025

Impact of social determinants of health on treatment patterns and outcomes in multiple myeloma.

Natalie Boytsov, Jasjit K Multani, Zifan Zhou, Nirali Kotowsky, Amanda Bolgioni-Smith, Tianyao Huo, Queenie Paltanwale, Simon McNamara, Chi-Chang Chen

Abstract read
In one paragraph

Article in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natalie BoytsovReal World Evidence & Health Outcomes Research, GSK, Upper Providence, PA, USA.
Jasjit K MultaniHealth Economics and Outcomes Research, IQVIA, Falls Church, VA, USA.ORCID 0000-0002-7886-6088
Zifan ZhouHealth Economics and Outcomes Research, IQVIA, Falls Church, VA, USA.
Nirali KotowskyReal World Evidence & Health Outcomes Research, GSK, San Francisco, CA, USA.
Amanda Bolgioni-SmithUS Medical Affairs, GSK, Waltham, MA, USA.ORCID 0000-0002-6910-9050
Tianyao HuoAdvanced Analytics, IQVIA, King of Prussia, PA, USA.
Queenie PaltanwaleHealth Economics and Outcomes Research, IQVIA, Durham, NC, USA.ORCID 0009-0003-2971-7304
Simon McNamaraReal World Evidence & Health Outcomes Research, GSK, Stevenage, Hertfordshire, UK.ORCID 0000-0003-1082-118X
Chi-Chang ChenHealth Economics and Outcomes Research, IQVIA, King of Prussia, PA, USA.ORCID 0000-0002-7065-9607

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsEvaluate treatment and outcomes by social determinants of health (SDoH) in multiple myeloma (MM), which are important for improving care and outcomes.

methodsThis was a retrospective study of real-world patients enrolled in a US insurance claims database (MM diagnosis, July 2018-December 2022) with linkage to a SDoH database, supplemented with mortality, provider affiliation (academic/community), and socioeconomically disadvantaged area databases. Treatment and outcomes were evaluated across SDoH domains: race/ethnicity, education level, transportation access, food insecurity, risky health behaviors, living in disadvantaged areas, healthcare needs, and ease of healthcare-systems engagement.

resultsThe study included 4768 patients (2295 and 2731 with care-setting and treatment data); median follow-up, 584 days. Patients treated in academic versus community settings were less likely to be food insecure and live in disadvantaged areas and had lower healthcare needs. Stem cell transplant was more common in White versus non-White patients, those with low versus high food insecurity and healthcare needs, and high versus low ease of healthcare-systems engagement. In multivariable analysis, high versus low disadvantaged areas (HR = 1.75) and medium versus low food insecurity (HR = 1.80) were associated with shorter overall survival.

conclusionsThese findings indicate a need for improved access to care in the broader MM population.

Indexed as

Multiple MyelomaSocial Determinants of HealthAdultAgedFemaleFood InsecurityHealthcare DisparitiesHealth Services AccessibilityHumansMaleMiddle AgedRetrospective StudiesSocioeconomic FactorsTreatment OutcomeUnited StatesHematologic/myelomaoutcomes researchreal-world evidencesocial determinants of healthtreatment patterns

Identifiers

PMID40351131
PMCPMC12140468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.