Trial reportPhysiological reports2025
Low-dose ASA therapy does not alter core or skin temperature during hot-dry or warm-humid heat stress (PSU HEAT project).
Trial report in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Low-dose ASA therapy does not alter core or skin temperature during hot-dry or warm-humid heat stress (PSU HEAT project).Physiological reports · 2025Trial
- Recognizing and Mitigating the Effects of Medication on Heat-Related Illness in Older Adults: A Scoping Review.Pharmacy (Basel, Switzerland) · 2026Review
- Identification of potentially heat-vulnerability increasing drugs - a narrative review.European journal of clinical pharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Nearly 40% of US adults over the age of 50 use aspirin (ASA) therapy for the primary or secondary prevention of cardiovascular disease. Systemic platelet cyclooxygenase inhibition with low-dose ASA attenuates reflex cutaneous vasodilation and accelerates the rate of rise of core temperature during passive heating in middle-aged adults. The functional effect of low-dose ASA therapy on thermoregulatory and cardiovascular responses to hot and humid environmental extremes in older (>65 years) adults has not been determined. Eleven older adults (5F; 66-80 years) were exposed to progressive heat stress in an environmental chamber at a metabolic rate comparable to activities of daily living (~80 W∙m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.