ArticleThe Journal of neuropsychiatry and clinical neurosciences2026
Suicidal Ideation in Spinocerebellar Ataxia.
Abstract read
In one paragraph
Article in The Journal of neuropsychiatry and clinical neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors.
Levi PeppelDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Ruo-Yah LaiDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Christian RummeyDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Puneet OpalDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Jeremy D SchmahmannDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Christopher M GomezDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Henry PaulsonDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Theresa A ZesiewiczDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Susan PerlmanDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
George WilmotDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Sarah H YingDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Chiadi U OnyikeDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Khalaf O BusharaDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Michael D GeschwindDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Karla P FigueroaDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Stefan M PulstDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Sub H SubramonyDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Antoine DuquetteDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Tetsuo AshizawaDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Ali G HamedaniDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Marie Y DavisDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Sharan R SrinivasanDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Matthew R BurnsDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Nadia AmokraneDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Lauren R MooreDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Vikram G ShakkottaiDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Liana S RosenthalDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Sheng-Han KuoDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Chi-Ying R LinDepartment of Neurology, Baylor College of Medicine, Houston (Peppel, Lin); Department of Neurology and Initiative of Columbia Ataxia and Tremor, Columbia University Medical Center, New York City (Lai, Amokrane, Kuo); Clinical Data Science GmbH, Basel, Switzerland (Rummey); Department of Neurology, Northwestern University, Chicago (Opal); Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston (Schmahmann); Department of Neurology, University of Chicago, Chicago (Gomez); Department of Neurology, University of Michigan, Ann Arbor (Paulson, Srinivasan); Department of Neurology, University of South Florida, Tampa (Zesiewicz); Department of Neurology, University of California, Los Angeles, Los Angeles (Perlman); Department of Neurology, Emory University, Atlanta (Wilmot); Departments of Psychiatry and Behavioral Sciences (Ying, Onyike) and Neurology (Rosenthal), Johns Hopkins University, Baltimore; Department of Neurology, University of Minnesota, Minneapolis (Bushara); Department of Neurology, University of California, San Francisco, San Francisco (Geschwind); Department of Neurology, University of Utah, Salt Lake City (Figueroa, Pulst); Department of Neurology, University of Florida, Gainesville (Subramony, Burns); Centre Hospitalier de l'Université de Montréal, University of Montreal, Montreal (Duquette); Houston Methodist Research Institute, Houston (Ashizawa); Departments of Neurology, Ophthalmology, and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Hamedani); Department of Neurology, University of Washington, Seattle (Davis); National Ataxia Foundation, Minneapolis (Moore); Department of Neurology, University of Texas Southwestern Medical Center, Dallas (Shakkottai).
Funding
Ataxin-2 complex proteins in neurodegeneration.R35NS127253 · NINDS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Stefan M. PULST · 2022 to 2026
$4.6MCognitive and Affective Network Dysfunction and Neuromodulation in Aging and SynucleinopathyK08AG071983 · NIA · UNIVERSITY OF FLORIDA · PI BURNS, MATTHEW ROBERT · 2021 to 2025
$772kNIA NIH HHS K08 AG071983NINDS NIH HHS R35 NS127253
Abstract
objectiveSuicidal ideation has not been extensively studied in spinocerebellar ataxias (SCAs). The authors examined whether individuals with SCAs have increased suicidal ideation and related factors.
methodsThe authors studied patients with genetically confirmed SCAs enrolled in the Clinical Research Consortium for the Study of Cerebellar Ataxia cohort, examining the percentages of patients with SCA subtypes 1, 2, 3, and 6 who reported suicidal ideation and comparing findings with nationally representative data from the National Survey on Drug Use and Health (NSDUH). Clinical characteristics that may contribute to suicidal ideation in SCAs, including age, disease duration, sex, ataxia severity, depression, and SCA subtype, were also studied.
resultsSuicidal ideation was present among 12% of 769 patients with SCAs and 4.3% of individuals in the general population recorded in the NSDUH. Compared with individuals in the general population, SCA patients had higher odds of suicidal ideation (OR=2.72). Compared with patients with SCA without suicidal ideation, patients with SCA and suicidal ideation had a longer disease duration (mean±SD=13.1±8.2 years vs. 11.2±9.4 years), more severe ataxia (Scale for the Assessment and Rating of Ataxia mean score=15.9±8.6 vs. 12.9±7.6), and more severe depression. Having suicidal ideation at baseline significantly increased the odds of suicidality later in the disease course (OR=58.73, 95% CI=36.00-98.40).
conclusionsSuicidal ideation was more prevalent among patients with SCAs than in the general population. The findings of this study underscore the importance of continuous suicidal risk screening among individuals with SCAs and the need for effective depression management.
Indexed as
Spinocerebellar AtaxiasSuicidal IdeationAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedSeverity of Illness IndexYoung AdultCerebellar DisordersCerebellumNonmotor FunctionSpinocerebellar AtaxiaSuicidal IdeationSuicide
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.