ArticleHand (New York, N.Y.)2026
The Highs and Lows of Fracture Fixation: Complications After Wrist Fracture Fixation for Users of Cannabis, Tobacco, or Neither Substance.
Article in Hand (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Functional Outcomes After Hip Arthroscopy Based on Self-Reported Cannabis Use: A Matched-Controlled Study.Orthopaedic journal of sports medicine · 2026Article
- Is Cannabis Dependence Associated with Postoperative Infections in Hand and Wrist Surgeries?Journal of hand surgery global online · 2026Article
- Cannabis and nicotine use are independently associated with adverse surgical, medical, and psychosocial outcomes following upper extremity fracture fixation.Journal of orthopaedic surgery and research · 2026Article
- Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated associations of cannabis and tobacco use with complications after open reduction and internal fixation (ORIF) of wrist fractures.
methodsWe retrospectively analyzed PearlDiver data from 337 538 patients who underwent ORIF for wrist fractures from 2010 to 2022. We identified 5587 patients with a history of cannabis use disorder ("cannabis group"); 12 806 patients with a history of tobacco use and no history of cannabis use disorder ("tobacco group"), and 310 108 patients with no history of cannabis use disorder or tobacco use ("control group"). We excluded patients with a history of using other illicit drugs. Propensity matching was used to control for age, sex, and comorbidity burden. Demographic characteristics, comorbidity profiles, and medical and surgical complications were compared using chi-squared tests. Complications were assessed within 90 days after surgery. Postoperative outcomes were also stratified by fracture location. Alpha = .05.
resultsCompared with the control group, the cannabis group had a significantly higher incidence of all medical complications and of fracture malunion, nerve injury, and tendon, muscle, or fascia injury. Compared with the tobacco group, the cannabis group had significantly lower incidence of sepsis, pneumonia, deep venous thrombosis, urinary tract infection, nerve injury, and wound dehiscence.
conclusionsCompared with nonusers of cannabis and tobacco, cannabis users had a higher incidence of several medical and surgical complications after ORIF for wrist fractures. These findings will help physicians better anticipate complications in patients who use cannabis or tobacco.
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