Evidence map›Paper›PMID 40350780›Full record

ArticleHand (New York, N.Y.)2026

The Highs and Lows of Fracture Fixation: Complications After Wrist Fracture Fixation for Users of Cannabis, Tobacco, or Neither Substance.

Arman Kishan, Victoria E Bergstein, Blake Prieskorn, Stanley Zhu, Ansh Kishan, Thomas P Cancian, Visakha Suresh, Pawel P Jankowski, Sami H Tuffaha, Dawn M LaPorte

Abstract read
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Article in Hand (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Arman KishanThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Victoria E BergsteinThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0009-0006-7332-2141
Blake PrieskornWest Virginia School of Osteopathic Medicine, Lewisburg, USA.
Stanley ZhuUniversity of Michigan Medical School, Ann Arbor, USA.
Ansh KishanK. J. Somaiya Institute of Technology, Mumbai, India.
Thomas P CancianThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Visakha SureshThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Pawel P JankowskiHoag Orthopedic Institute, Irvine, CA, USA.
Sami H TuffahaThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Dawn M LaPorteThe Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-6564-2707

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated associations of cannabis and tobacco use with complications after open reduction and internal fixation (ORIF) of wrist fractures.

methodsWe retrospectively analyzed PearlDiver data from 337 538 patients who underwent ORIF for wrist fractures from 2010 to 2022. We identified 5587 patients with a history of cannabis use disorder ("cannabis group"); 12 806 patients with a history of tobacco use and no history of cannabis use disorder ("tobacco group"), and 310 108 patients with no history of cannabis use disorder or tobacco use ("control group"). We excluded patients with a history of using other illicit drugs. Propensity matching was used to control for age, sex, and comorbidity burden. Demographic characteristics, comorbidity profiles, and medical and surgical complications were compared using chi-squared tests. Complications were assessed within 90 days after surgery. Postoperative outcomes were also stratified by fracture location. Alpha = .05.

resultsCompared with the control group, the cannabis group had a significantly higher incidence of all medical complications and of fracture malunion, nerve injury, and tendon, muscle, or fascia injury. Compared with the tobacco group, the cannabis group had significantly lower incidence of sepsis, pneumonia, deep venous thrombosis, urinary tract infection, nerve injury, and wound dehiscence.

conclusionsCompared with nonusers of cannabis and tobacco, cannabis users had a higher incidence of several medical and surgical complications after ORIF for wrist fractures. These findings will help physicians better anticipate complications in patients who use cannabis or tobacco.

Indexed as

Fracture Fixation, InternalFractures, BoneMarijuana AbuseOpen Fracture ReductionPostoperative ComplicationsWrist InjuriesAdultAgedFemaleHumansIncidenceMaleMiddle AgedRetrospective Studiescannabiscomplicationshand fractureopen reduction and internal fixationtobaccowrist fracture

Identifiers

PMID40350780
PMCPMC12069308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.