Evidence map›Paper›PMID 40350708›Full record

ReviewJournal of gynecologic oncology2025

The past, present, and future of FIGO staging of endometrial cancer.

Xiaoyan Zhao, Fujing Sun, Nankun Leng, Xin Zhang, Yanmei Zhu

Abstract readReview
In one paragraph

Review in Journal of gynecologic oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. m6A modification and its clinical applications in gynaecological cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoyan ZhaoDepartment of Gynecology, Affiliated Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.ORCID 0009-0000-8866-3850
Fujing SunDepartment of Pathology, Affiliated Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.ORCID 0009-0003-3315-0849
Nankun LengDepartment of Gynecology, Affiliated Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China.ORCID 0009-0002-3718-9954
Xin ZhangDepartment of Gynecology, Affiliated Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China. zhangxiangmiao@hotmail.com.ORCID 0000-0002-4743-2578
Yanmei ZhuDepartment of Pathology, Affiliated Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital and Institute, Cancer Hospital of China Medical University, Shenyang, China. zhuyanmei@cancerhosp-ln-cmu.com.ORCID 0000-0001-5526-7624

Funding

Fundamental Research Funds for the Central Universities LD2023010Fundamental Research Funds for the Central Universities LD2023017Fundamental Research Funds for the Central Universities LD2023019Liaoning Provincial Natural Science Foundation 2024-MS-271
6 · The paper itself

Abstract

The International Federation of Gynecology and Obstetrics (FIGO) staging of endometrial cancer (EC) is regarded as a crucial tool for guiding treatment, evaluating prognosis, and advancing clinical research. It is a concept of shared importance among gynecologic oncologists, pathologists, and patients with EC. In June 2023, the International Federation of Gynecology and Obstetrics released a new staging system for EC. This review aims to discuss comprehensively the developmental trajectory of FIGO staging for EC, focusing on the differences between the 2023 FIGO and earlier staging systems, and delineating the advantages and disadvantages of incorporating various pathological factors and molecular subtypes into staging. The article emphasizes the progress made with the updated 2023 FIGO version in improving prognostic prediction accuracy for patients with EC. However, as the staging categories expand, their complexity becomes increasingly apparent, potentially impacting health care professionals' accurate understanding and application of staging. Moreover, unresolved issues persist regarding histological types and grading, lymphovascular space invasion, and molecular subtypes, as well as distinguishing between low-grade endometrioid carcinomas confined to the uterus and ovaries, which may affect the personalized management of patients with EC. In the future, these issues still require extensive clinical research and specific data for validation or confirmation, presenting a challenge shared by gynecologic oncologists and pathologists.

Indexed as

Endometrial NeoplasmsNeoplasm StagingFemaleHumansPrognosisEndometrial CancerFIGOMolecular TypingNeoplasm Staging

Identifiers

PMID40350708
PMCPMC12226330

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.